Three-dimensional (3D) in vitro models, such as organ-on-a-chip platforms, are an emerging
and effective technology that allows the replication of the function of tissues and organs …

Drug evaluation has always been an important area of research in the pharmaceutical
industry. However, animal welfare protection and other shortcomings of traditional drug …

Vascularization of 3D models represents a major challenge of tissue engineering and a key
prerequisite for their clinical and industrial application. The use of prevascularized models …

Microfluidic technology is a relatively new field among the various conventional bulk
techniques employed for nanomaterial synthesis. Nanoparticles (NPs) produced using such …

As a full-fidelity simulation of human cells, tissues, organs, and even systems at the
microscopic scale, Organ-on-a-Chip (OOC) has significant ethical advantages and …

Cancer immunotherapy is the great breakthrough in cancer treatment as it displayed
prolonged progression-free survival over conventional therapies, yet, to date, in only a …

New drug discovery is under growing pressure to satisfy the demand from a wide range of
domains, especially from the pharmaceutical industry and healthcare services. Assessment …

Disorders of the synovial joint, such as osteoarthritis (OA) and rheumatoid arthritis (RA),
afflict a substantial proportion of the global population. However, current clinical …

Parkinson's disease (PD) is one of the most prevalent neurodegenerative diseases. The
typical symptomatology of PD includes motor symptoms; however, a range of nonmotor …

There is a growing interest to understand if and how the gut microbiome is causally linked to
the pathogenesis and/or progression of diseases. While in vitro cell line models are …