Skeletal infections: microbial pathogenesis, immunity and clinical management

EA Masters, BF Ricciardi, KLM Bentley… - Nature Reviews …, 2022 - nature.com
Osteomyelitis remains one of the greatest risks in orthopaedic surgery. Although many
organisms are linked to skeletal infections, Staphylococcus aureus remains the most …

Acne, microbiome, and probiotics: The gut–skin axis

P Sánchez-Pellicer, L Navarro-Moratalla… - Microorganisms, 2022 - mdpi.com
The objective of this narrative review was to check the influence of the human microbiota in
the pathogenesis of acne and how the treatment with probiotics as adjuvant or alternative …

[HTML][HTML] Acne vulgaris: A review of the pathophysiology, treatment, and recent nanotechnology based advances

M Vasam, S Korutla, RA Bohara - Biochemistry and Biophysics Reports, 2023 - Elsevier
Abstract Background Globally, Acne Vulgaris is a widespread, chronic inflammatory
condition of the pilosebaceous follicles. Acne is not fatal, but depending on its severity, it can …

From Dysbiosis to Healthy Skin: Major Contributions of Cutibacterium acnes to Skin Homeostasis

M Rozas, A Hart de Ruijter, MJ Fabrega, A Zorgani… - Microorganisms, 2021 - mdpi.com
Cutibacterium acnes is the most abundant bacterium living in human, healthy and sebum-
rich skin sites, such as the face and the back. This bacterium is adapted to this specific …

Skin dysbiosis and Cutibacterium acnes biofilm in inflammatory acne lesions of adolescents

I Cavallo, F Sivori, M Truglio, F De Maio, F Lucantoni… - Scientific Reports, 2022 - nature.com
Acne vulgaris is a common inflammatory disorder affecting more than 80% of young
adolescents. Cutibacterium acnes plays a role in the pathogenesis of acne lesions, although …

[HTML][HTML] Oxidative stress and metabolic syndrome in acne vulgaris: Pathogenetic connections and potential role of dietary supplements and phytochemicals

AF Bungau, AF Radu, SG Bungau, CM Vesa… - Biomedicine & …, 2023 - Elsevier
Acne vulgaris is a highly prevalent skin condition caused by androgen-induced elevated
sebum secretion, abnormal keratinization, bacterial colonization, and inflammation. Current …

A Janus-Faced Bacterium: Host-Beneficial and -Detrimental Roles of Cutibacterium acnes

H Brüggemann, L Salar-Vidal, HPM Gollnick… - Frontiers in …, 2021 - frontiersin.org
The bacterial species Cutibacterium acnes (formerly known as Propionibacterium acnes) is
tightly associated with humans. It is the dominant bacterium in sebaceous regions of the …

Recent advances in understanding inflammatory acne: Deciphering the relationship between Cutibacterium acnes and Th17 inflammatory pathway

C Mias, V Mengeaud, S Bessou‐Touya… - Journal of the …, 2023 - Wiley Online Library
Acne vulgaris is a common chronic inflammatory skin disease of the pilosebaceous units.
Four factors contribute to acne: hyperseborrhea and dysseborrhea, follicular …

Acne transcriptomics: fundamentals of acne pathogenesis and isotretinoin treatment

BC Melnik - Cells, 2023 - mdpi.com
This review on acne transcriptomics allows for deeper insights into the pathogenesis of acne
and isotretinoin's mode of action. Puberty-induced insulin-like growth factor 1 (IGF-1), insulin …

Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease

X Zhou, X Shen, JS Johnson, DJ Spakowicz… - Cell Host & Microbe, 2024 - cell.com
To understand the dynamic interplay between the human microbiome and host during
health and disease, we analyzed the microbial composition, temporal dynamics, and …