Advances in aldo-keto reductases immobilization for biocatalytic synthesis of chiral alcohol
W Zhang, ZQ Shao, ZX Wang, YF Ye, SF Li… - International Journal of …, 2024 - Elsevier
Chiral alcohols are essential building blocks of numerous pharmaceuticals and fine
chemicals. Aldo-keto reductases (AKRs) constitute a superfamily of oxidoreductases that …
chemicals. Aldo-keto reductases (AKRs) constitute a superfamily of oxidoreductases that …
Computer‐directed rational design enhanced the thermostability of carbonyl reductase LsCR for the synthesis of ticagrelor precursor
SY Xu, RL Chu, HT Liu, CY Weng… - Biotechnology and …, 2024 - Wiley Online Library
Carbonyl reductases are useful for producing optically active alcohols from their
corresponding prochiral ketones. Herein, we applied a computer‐assisted strategy to …
corresponding prochiral ketones. Herein, we applied a computer‐assisted strategy to …
Structural insights into the distinct substrate preferences of two bacterial epoxide hydrolases
Epoxide hydrolases (EHs), which catalyze the transformation of epoxides to diols, are
present in many eukaryotic and prokaryotic organisms. They have recently drawn …
present in many eukaryotic and prokaryotic organisms. They have recently drawn …
Computer‐aided design to enhance the stability of aldo‐keto reductase KdAKR
C Dai, JX Tian, YF Chen, YH Ni, L Cui… - Biotechnology …, 2024 - Wiley Online Library
The aldo‐keto reductase (AKR) KdAKR from Kluyvermyces dobzhanskii can reduce t‐butyl 6‐
chloro‐(5S)‐hydroxy‐3‐oxohexanoate ((5S)‐CHOH) to t‐butyl 6‐chloro‐(3R, 5S) …
chloro‐(5S)‐hydroxy‐3‐oxohexanoate ((5S)‐CHOH) to t‐butyl 6‐chloro‐(3R, 5S) …
Anticandidal applications of selenium nanoparticles biosynthesized with Limosilactobacillus fermentum (OR553490)
EA Mohamed, MM El‑Zahed - Discover Nano, 2024 - Springer
Candida albicans is one of the most dangerous pathogenic fungi in the world, according to
the classification of the World Health Organization, due to the continued development of its …
the classification of the World Health Organization, due to the continued development of its …