Pulmonary diseases due to mycobacteria cause significant morbidity and mortality to human
health. In addition to tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), recent …

Despite co-evolving with humans for centuries and being intensely studied for decades, the
immune correlates of protection against Mycobacterium tuberculosis (Mtb) have yet to be …

Tuberculosis (TB) is reported as one of the most prevailing life-threatening health problems,
affecting almost one third of the population globally. It is one of a major reason of death with …

Abstract Bacillus Calmette–Guérin (BCG), the only vaccine proven to be effective against
tuberculosis (TB), is the most commonly used vaccine globally. In addition to its effects on …

Tuberculosis (TB), also known as the “White Plague”, is caused by Mycobacterium
tuberculosis (Mtb). Before the COVID-19 epidemic, TB had the highest mortality rate of any …

The World Health Organization (WHO) herald of the “End TB Strategy” has defined goals
and targets for tuberculosis prevention, care, and control to end the global tuberculosis …

GamTBvac is a candidate tuberculosis vaccine with two fusion proteins, containing Ag85a,
ESAT6, CFP10, and a dextran-binding domain (DBD). Phase II of a double-blind …

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb) that
sits in the top 10 leading causes of death in the world today and is the current leading cause …

Heterologous vaccine regimens could extend waning protection in the global population
immunized with Mycobacterium bovis Bacille Calmette-Guerin (BCG). We demonstrate that …

Vaccinations, especially DNA vaccines that promote host immunity, are the most effective
interventions for tuberculosis (TB) control. However, the vaccine delivery system exhibits a …