Neisseria meningitidis is the main cause of meningitis and sepsis, potentially life-threatening
conditions. Thanks to advancements in vaccine development, vaccines are now available …

Complement is a complex protein network of plasma, and an integral part of the innate
immune system. Complement activation results in the rapid clearance of bacteria by immune …

Abstract Background In September 2015, the United Kingdom introduced the
multicomponent meningococcal group B vaccine (4CMenB, Bexsero) into its publicly funded …

Infections with Neisseria meningitidis and Neisseria gonorrhoeae have different clinical
manifestations, but the bacteria share up to 80–90% genome sequence identity. The …

Exosomes are cell-derived components composed of proteins, lipid, genetic information,
cytokines, and growth factors. They play a vital role in immune modulation, cell-cell …

Acinetobacter baumannii exhibits resistance to most first-line antibiotics; thus, development
of new antibacterial agents is urgently required. Pseudaminic acid exists as the surface …

Streptococcus pneumoniae remains a deadly disease in small children and the elderly even
though conjugate and polysaccharide vaccines based on isolated capsular polysaccharides …

Introduction: Three major advances have led to increase in length and quality of human life:
increased food production, improved sanitation and induction of specific adaptive immune …

Signs and symptoms of meningeal inflammation have been recorded in countless ancient
texts throughout history; however, the term'meningitis' came into general usage after …

Chemical synthesis is a powerful tool to access homogeneous complex glycans, which
relies on protecting group (PG) chemistry. However, the overall efficiency of chemical glycan …