While great progress has been made in the understanding of neurological illnesses, the
pathologies, and etiologies that give rise to these diseases still remain an enigma, thus, also …

The assessment of pain, distress and suffering, as well as evaluation of the efficacy of stress-
reduction strategies, is crucial in animal experimentation but can be challenging in …

Alzheimer's disease (AD) is the most common neurodegenerative disease in the United
States (US). Animal models, specifically mouse models have been developed to better …

Transgenic mouse models have been used extensively to model the cognitive impairments
arising from Alzheimer's disease (AD)-related pathology. However, less is known about the …

The ability to identify strange conspecifics in societies is supported by social memory, which
is vital for gregarious animals and humans. The function of hippocampal principal neurons …

Introduction: Memory is defined as the ability to store, maintain and retrieve information.
Learning is the acquisition of information that changes behavior and memory. Stress …

Parkinson's disease (PD) is a neurodegenerative disease that is accompanied with the loss
of dopaminergic neurons in the substantia nigra pars compacta which subsequently leads to …

Three common dosing regimens of the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine
(MPTP)-induced model of Parkinson's disease (PD) were compared in C57BL/6 mice on …

Parvalbumin (PV)-expressing interneurons which are often associated with the specific
extracellular matrix perineuronal net (PNN) play a critical role in the alteration of brain …

Mangiferin, a polyphenol compound of C-glucoside, is well-known for its anti-inflammatory,
antioxidant, anticancer, antidiabetic and cognitive enhancement properties. In this study, we …