Curcumin: a phytochemical modulator of estrogens and androgens in tumors of the reproductive system

M Mohajeri, V Bianconi, MF Ávila-Rodriguez… - Pharmacological …, 2020 - Elsevier
Curcumin (Cur) is an active derivative extracted from turmeric which exerts a wide range of
interactions with biomolecules through complex signaling pathways. Cur has been …

Sentinel lymph node biopsy in patients with ductal carcinoma in situ: systematic review and meta-analysis

MG Davey, C O'Flaherty, EF Cleere, A Nohilly… - BJS open, 2022 - academic.oup.com
Background Axillary lymph node status remains the most powerful prognostic indicator in
invasive breast cancer. Ductal carcinoma in situ (DCIS) is a non-invasive disease and does …

The effects of turmeric (curcumin) on tumor suppressor protein (p53) and estrogen receptor (ERα) in breast cancer cells

K Hallman, K Aleck, B Dwyer, V Lloyd… - … Cancer: Targets and …, 2017 - Taylor & Francis
Curcumin (CUR) is a compound that has antibacterial, antiviral, anti-inflammatory, and
anticancer properties. In this study, we have analyzed the effects of CUR on the expression …

3D tumor models for breast cancer: Whither we are and what we need

GM Balachander, R Kotcherlakota… - ACS Biomaterials …, 2021 - ACS Publications
Three-dimensional (3D) models have led to a paradigm shift in disease modeling in vitro,
particularly for cancer. The past decade has seen a phenomenal increase in the …

[HTML][HTML] High-content stimulated Raman histology of human breast cancer

H Ni, CP Dessai, H Lin, W Wang, S Chen, Y Yuan… - Theranostics, 2024 - ncbi.nlm.nih.gov
Histological examination is crucial for cancer diagnosis, however, the labor-intensive
sample preparation involved in the histology impedes the speed of diagnosis. Recently …

Breast conservation in ductal carcinoma in situ (DCIS): what defines optimal margins?

MS Toss, SE Pinder, AR Green, J Thomas… - …, 2017 - Wiley Online Library
The introduction of mammographic screening has resulted in a rise in the detection rate of
ductal carcinoma in situ (DCIS), currently accounting for one‐fifth of screen‐detected breast …

[HTML][HTML] MiRNA expression deregulation correlates with the Oncotype DX® DCIS score

O Loudig, MI Mitchell, IZ Ben-Dov, C Liu… - Breast Cancer …, 2022 - Springer
Background Current clinical criteria do not discriminate well between women who will or
those who will not develop ipsilateral invasive breast cancer (IBC), or a DCIS recurrence …

The regulation of steroid receptors by epigallocatechin-3-gallate in breast cancer cells

K Hallman, K Aleck, M Quigley, B Dwyer… - … Cancer: Targets and …, 2017 - Taylor & Francis
It has been reported that phytoestrogen epigallocatechin gallate (EGCG) suppresses cancer
cell proliferation and may have antitumor properties. In this study, we analyzed the effects of …

The antiestrogenic effects of black cohosh on BRCA1 and steroid receptors in breast cancer cells

M Crone, K Hallman, V Lloyd, M Szmyd… - … Cancer: Targets and …, 2019 - Taylor & Francis
Background Black cohosh (BC) is an herbal remedy often used by women to treat symptoms
associated with menopause. Research has shown that the molecular activity of BC is …

PVCP-based anthropomorphic breast phantoms containing structures similar to lactiferous ducts for ultrasound imaging: a comparison with human breasts

LL De Matheo, J Geremia, MJG Calas… - Ultrasonics, 2018 - Elsevier
The purpose of this work was to obtain an anthropomorphic phantom with acoustic
properties similar to those of breast tissue, possessing lactiferous duct-like structures, which …