[HTML][HTML] COVID-19 infection and liver injury: Clinical features, biomarkers, potential mechanisms, treatment, and management challenges

GR Sivandzadeh, H Askari, AR Safarpour… - World journal of …, 2021 - ncbi.nlm.nih.gov
It is hypothesized that liver impairment caused by coronavirus disease 2019 (COVID-19)
infection might play a central role in severe clinical presentations. Liver injury is closely …

Exploration of Emodin to treat alpha-naphthylisothiocyanate-induced cholestatic hepatitis via anti-inflammatory pathway

Y Ding, L Zhao, H Mei, SL Zhang, ZH Huang… - European Journal of …, 2008 - Elsevier
Emodin, 1, 3, 8-trihydroxy-6-methyl-anthraquinone, is an anthraquinone derivative from the
roots of Rheum officinale Baill that has been used to treat many diseases in digestive system …

Polyphenols extracted from Enteromorpha clathrata alleviates inflammation in lipopolysaccharide-induced RAW 264.7 cells by inhibiting the MAPKs/NF-κB signaling …

P Huang, J Hong, J Mi, B Sun, J Zhang, C Li… - Journal of …, 2022 - Elsevier
Ethnopharmacology relevance Enteromorpha has long been recorded in traditional Chinese
medicine, with cholesterol-lowering, anti-cancer, anti-inflammatory and antibacterial effects …

[HTML][HTML] Betulinic acid attenuates dexamethasone-induced oxidative damage through the JNK-P38 MAPK signaling pathway in mice

L Zhu, X Yi, J Zhao, Z Yuan, L Wen, B Pozniak… - Biomedicine & …, 2018 - Elsevier
Dexamethasone (Dex), a potent anti-inflammatory/immunosuppressive agent, has been
shown to induce oxidative stress. Betulinic acid (BA) is a pentacyclic lupane triterpene with a …

[HTML][HTML] Effects of steroid growth promoter on morphological and biochemical adaptations in liver of broiler

N Sultana, M Afrose, K Rafiq - Veterinary World, 2020 - ncbi.nlm.nih.gov
Aim: The study was conducted to observe the effects of dexamethasone (DEX) on the gross
study and histomorphometry of liver and on the alterations of biochemical parameters of …

[HTML][HTML] Coriander essential oil attenuates dexamethasone-induced acute liver injury through potentiating Nrf2/HO-1 and ameliorating apoptotic signaling

MF Mahmoud, N Ali, I Mahdi, O Mouhtady… - Journal of Functional …, 2023 - Elsevier
Coriander essential oil extracted from the fruits of Coriandrum sativum is rich in linalool, γ-
terpinene and α-pinene. Herein we examined the possible hepatoprotective effects of …

Simultaneous administration of dexamethasone and vitamin E reversed experimental varicocele-induced impact in testicular tissue in rats; correlation with Hsp70-2 …

H Khosravanian, M Razi, F Farokhi… - International braz j …, 2015 - SciELO Brasil
Purpose: This study aimed to investigate the protective effects of isolated and co-
administration of vitamin E (VitE) and dexamethasone (DEX) on varicocele (VCL)-induced …

Glucocorticoids have opposing effects on liver fibrosis in hepatic stellate and immune cells

KH Kim, JM Lee, Y Zhou, S Harpavat… - Molecular …, 2016 - academic.oup.com
Liver fibrosis is a reversible wound-healing process that is protective in the short term, but
prolonged fibrotic responses lead to excessive accumulation of extracellular matrix …

Microfluidic Human Physiomimetic Liver Model as a Screening Platform for Drug Induced Liver Injury

S Dey, A Bhat, G Janani, V Shandilya, R Gupta… - Biomaterials, 2024 - Elsevier
The pre-clinical animal models often fail to predict intrinsic and idiosyncratic drug induced
liver injury (DILI), thus contributing to drug failures in clinical trials, black box warnings and …

The effects of chitosan and low dose dexamethasone on extrahepatic cholestasis after bile duct ligation in Wistar rats

D Olteanu, A Filip, A Mureşan, A Nagy… - Acta Physiologica …, 2012 - akjournals.com
Inflammation and oxidative stress are important pathways in the development of liver fibrosis
following biliary obstruction. Aim: To evaluate the effects of low dose dexamethasone and …