Secretion systems in Gram-negative bacteria: structural and mechanistic insights

TRD Costa, C Felisberto-Rodrigues, A Meir… - Nature Reviews …, 2015 - nature.com
Bacteria have evolved a remarkable array of sophisticated nanomachines to export various
virulence factors across the bacterial cell envelope. In recent years, considerable progress …

Aim, load, fire: the type VI secretion system, a bacterial nanoweapon

FR Cianfanelli, L Monlezun, SJ Coulthurst - Trends in microbiology, 2016 - cell.com
Bacteria utilise specialised protein secretion systems to interact with host organisms,
competitor bacteria, and the environment. The Type VI secretion system (T6SS) is a versatile …

[PDF][PDF] A view to a kill: the bacterial type VI secretion system

BT Ho, TG Dong, JJ Mekalanos - Cell host & microbe, 2014 - cell.com
The bacterial type VI secretion system (T6SS) is an organelle that is structurally and
mechanistically analogous to an intracellular membrane-attached contractile phage tail …

PAAR-repeat proteins sharpen and diversify the type VI secretion system spike

MM Shneider, SA Buth, BT Ho, M Basler, JJ Mekalanos… - Nature, 2013 - nature.com
The bacterial type VI secretion system (T6SS) is a large multicomponent, dynamic
macromolecular machine that has an important role in the ecology of many Gram-negative …

[PDF][PDF] A type VI secretion-related pathway in Bacteroidetes mediates interbacterial antagonism

AB Russell, AG Wexler, BN Harding, JC Whitney… - Cell host & …, 2014 - cell.com
Bacteroidetes are a phylum of Gram-negative bacteria abundant in mammalian-associated
polymicrobial communities, where they impact digestion, immunity, and resistance to …

Type VI secretion systems in plant‐associated bacteria

P Bernal, MA Llamas, A Filloux - Environmental microbiology, 2018 - Wiley Online Library
The type VI secretion system (T6SS) is a bacterial nanomachine used to inject effectors into
prokaryotic or eukaryotic cells and is thus involved in both host manipulation and …

Biogenesis and structure of a type VI secretion membrane core complex

E Durand, VS Nguyen, A Zoued, L Logger… - Nature, 2015 - nature.com
Bacteria share their ecological niches with other microbes. The bacterial type VI secretion
system is one of the key players in microbial competition, as well as being an important …

[PDF][PDF] Type VI secretion systems of pathogenic and commensal bacteria mediate niche occupancy in the gut

A Serapio-Palacios, SE Woodward, SL Vogt, W Deng… - Cell Reports, 2022 - cell.com
The type VI secretion system (T6SS) is a contractile nanomachine widely distributed among
pathogenic and commensal Gram-negative bacteria. The T6SS is used for inter-bacterial …

Structure and regulation of the type VI secretion system

JM Silverman, YR Brunet, E Cascales… - Annual review of …, 2012 - annualreviews.org
The type VI secretion system (T6SS) is a complex and widespread gram-negative bacterial
export pathway with the capacity to translocate protein effectors into a diversity of target cell …

[HTML][HTML] Architecture and assembly of the Type VI secretion system

A Zoued, YR Brunet, E Durand, MS Aschtgen… - … et Biophysica Acta (BBA …, 2014 - Elsevier
The Type VI secretion system (T6SS) delivers protein effectors to diverse cell types including
prokaryotic and eukaryotic cells, therefore it participates in inter-bacterial competition and …