Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation
JAHR Claassen, DHJ Thijssen… - Physiological …, 2021 - journals.physiology.org
Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …
Losing the dogmatic view of cerebral autoregulation
Abstract In 1959, Niels Lassen illustrated the cerebral autoregulation curve in the classic
review article entitled Cerebral Blood Flow and Oxygen Consumption in Man. This concept …
review article entitled Cerebral Blood Flow and Oxygen Consumption in Man. This concept …
Unique spatiotemporal fMRI dynamics in the awake mouse brain
Human imaging studies have shown that spontaneous brain activity exhibits stereotypic
spatiotemporal reorganization in awake, conscious conditions with respect to minimally …
spatiotemporal reorganization in awake, conscious conditions with respect to minimally …
Metal–Organic Frameworks‐Based Nanoplatforms for the Theranostic Applications of Neurological Diseases
H Niu, H Bu, J Zhao, Y Zhu - Small, 2023 - Wiley Online Library
Neurological diseases are the foremost cause of disability and the second leading cause of
death worldwide. Owing to the special microenvironment of neural tissues and biological …
death worldwide. Owing to the special microenvironment of neural tissues and biological …
Distinct signatures of calcium activity in brain mural cells
Pericytes have been implicated in various neuropathologies, yet little is known about their
function and signaling pathways in health. Here, we characterized calcium dynamics of …
function and signaling pathways in health. Here, we characterized calcium dynamics of …
[HTML][HTML] Role of gut microbiota in neuropathy and neuropathic pain states: A systematic preclinical review
K Pane, S Boccella, F Guida, M Franzese… - Neurobiology of …, 2022 - Elsevier
Gut microbiota has implications in Central Nervous System (CNS) disorders. Our study
systematically identified preclinical studies aimed to investigate the possible gut microbiota …
systematically identified preclinical studies aimed to investigate the possible gut microbiota …
Ketamine in acute phase of severe traumatic brain injury “an old drug for new uses?”
Maintaining an adequate level of sedation and analgesia plays a key role in the
management of traumatic brain injury (TBI). To date, it is unclear which drug or combination …
management of traumatic brain injury (TBI). To date, it is unclear which drug or combination …
Perioperative stroke
JP Fanning, BCV Campbell, R Bulbulia… - Nature Reviews …, 2024 - nature.com
Ischaemic or haemorrhagic perioperative stroke (that is, stroke occurring during or within 30
days following surgery) can be a devastating complication following surgery. Incidence is …
days following surgery) can be a devastating complication following surgery. Incidence is …
Clinical outcomes after traumatic brain injury and exposure to extracranial surgery: a TRACK-TBI Study
CJ Roberts, J Barber, NR Temkin, A Dong… - JAMA …, 2024 - jamanetwork.com
Importance Traumatic brain injury (TBI) is associated with persistent functional and cognitive
deficits, which may be susceptible to secondary insults. The implications of exposure to …
deficits, which may be susceptible to secondary insults. The implications of exposure to …
The role of deep hypothermia in cardiac surgery
R Gocoł, D Hudziak, J Bis, K Mendrala… - International journal of …, 2021 - mdpi.com
Hypothermia is defined as a decrease in body core temperature to below 35° C. In cardiac
surgery, four stages of hypothermia are distinguished: mild, moderate, deep, and profound …
surgery, four stages of hypothermia are distinguished: mild, moderate, deep, and profound …