Mannose-binding lectin (MBL) is an innate immune system pattern recognition protein that
kills a wide range of pathogenic microbes through complement activation. A substantial …

Reduced levels of wild-type mannose-binding lectin (MBL) may increase susceptibility for
infection, other common diseases, and death. We investigated associations between MBL …

Background Genetic determinants of susceptibility to severe acute respiratory syndrome
coronavirus (SARS-CoV) infection remain unknown. We assessed whether mannose …

Several genes have been demonstrated to affect disease severity in CF. Furthermore, it is
likely that gene–gene and gene–environment interactions can explain a substantial portion …

Background Mannose binding lectin (MBL) is an important host defence protein against
opportunistic fungal pathogens. This carbohydrate-binding protein, an opsonin and lectin …

Mannose-binding lectin (MBL) and lectin complement pathway have become targets of
increasing clinical interest. Many aspects of MBL have been recently explored, including the …

An improved understanding of the pathogenesis of Aspergillus infections has facilitated the
identification of host biomarkers that, if validated in well-designed prospective studies, could …

Mesenchymal stromal cells (MSCs) are used to treat infectious and immune diseases and
disorders; however, its mechanism (s) remain incompletely defined. Here we find that bone …

In 2015, there were an estimated 10.4 million new cases of tuberculosis (TB) globally,
making it one of the leading causes of death due to an infectious disease. TB is caused by …

Collectins are collagen-containing C-type (calcium-dependent) lectins which are important
pathogen pattern recognising innate immune molecules. Their primary structure is …