Complement-mediated neutralization of dengue virus requires mannose-binding lectin

P Avirutnan, RE Hauhart, MA Marovich, P Garred… - MBio, 2011 - Am Soc Microbiol
Mannose-binding lectin (MBL) is a key soluble pathogen recognition protein of the innate
immune system that binds specific mannose-containing glycans on the surfaces of microbial …

Binding of mannose‐binding lectin to fructosamines: a potential link between hyperglycaemia and complement activation in diabetes

J Fortpied, D Vertommen… - … research and reviews, 2010 - Wiley Online Library
Background Complement activation via the MBL pathway has been proposed to play a role
in the pathogenesis of diabetic complications. As protein glycation is increased in diabetes …

Mannose binding lectin is required for alphavirus-induced arthritis/myositis

BM Gunn, TE Morrison, AC Whitmore, LK Blevins… - PLoS …, 2012 - journals.plos.org
Mosquito-borne alphaviruses such as chikungunya virus and Ross River virus (RRV) are
emerging pathogens capable of causing large-scale epidemics of virus-induced arthritis and …

Mannose‐binding lectin: biologic characteristics and role in the susceptibility to infections and ischemia‐reperfusion related injury in critically ill neonates

C Auriti, G Prencipe, M Moriondo… - Journal of …, 2017 - Wiley Online Library
The mannose‐binding lectin (MBL) is a member of the collectin family, belonging to the
innate immunity system. Genetic, biologic, and clinical properties of MBL have been widely …

Animal models: an important tool in mycology

J Capilla, KV Clemons, DA Stevens - Medical mycology, 2007 - academic.oup.com
Animal models of fungal infections are, and will remain, a key tool in the advancement of the
medical mycology. Many different types of animal models of fungal infection have been …

Polymorphisms in the MBL2 gene are associated with the plasma levels of MBL and the cytokines IL-6 and TNF-α in severe COVID-19

MAF Queiroz, AM Santiago, WRS Brito… - Frontiers in …, 2023 - frontiersin.org
Introduction Mannose-binding lectin (MBL) promotes opsonization, favoring phagocytosis
and activation of the complement system in response to different microorganisms, and may …

[HTML][HTML] Mannan-binding lectin pathway deficiencies and invasive fungal infections following allogeneic stem cell transplantation

M Granell, A Urbano-Ispizua, B Suarez, M Rovira… - Experimental …, 2006 - Elsevier
OBJECTIVE: The Mannan-binding lectin (MBL) pathway involves recognition of fungal
surfaces by MBL and cleavage of C2 and C4 by MBL-associated serine protease (namely …

Variant G57E of Mannose Binding Lectin Associated with Protection against Tuberculosis Caused by Mycobacterium africanum but not by M. tuberculosis

T Thye, S Niemann, K Walter, S Homolka… - PloS one, 2011 - journals.plos.org
Structural variants of the Mannose Binding Lectin (MBL) cause quantitative and qualitative
functional deficiencies, which are associated with various patterns of susceptibility to …

Three novel single-nucleotide polymorphisms of MBL1 gene in Chinese native cattle and their associations with milk performance traits

C Wang, M Liu, Q Li, Z Ju, J Huang, J Li, H Wang… - Veterinary immunology …, 2011 - Elsevier
Mannan-binding lectin (MBL), a pattern recognizing serum protein, participates in the innate
immune system of mammals as an opsonin. In humans, single-nucleotide polymorphisms …

Serum mannose-binding lectin (MBL) gene polymorphism and low MBL levels are associated with neonatal sepsis and pneumonia

H Özkan, N Köksal, M Çetinkaya, S Çelebi… - Journal of …, 2012 - nature.com
Objective: The aim of this study was to determine the serum mannose-binding lectin (MBL)
levels and the frequency of MBL gene polymorphisms in infants with neonatal sepsis. Study …