Sexual dimorphism in cardiometabolic health: the role of adipose tissue, muscle and liver

GH Goossens, JWE Jocken, EE Blaak - Nature Reviews Endocrinology, 2021 - nature.com
Obesity is associated with many adverse health effects, such as an increased
cardiometabolic risk. Despite higher adiposity for a given BMI, premenopausal women are at …

Gender and sex differences in adipose tissue

E Chang, M Varghese, K Singer - Current diabetes reports, 2018 - Springer
Abstract Purpose of Review As the ongoing epidemic of adult and childhood obesity grows,
it puts a greater burden on individuals and the healthcare system due to increased …

Pathophysiology of human visceral obesity: an update

A Tchernof, JP Després - Physiological reviews, 2013 - journals.physiology.org
Excess intra-abdominal adipose tissue accumulation, often termed visceral obesity, is part of
a phenotype including dysfunctional subcutaneous adipose tissue expansion and ectopic …

Sex differences in human adipose tissues–the biology of pear shape

K Karastergiou, SR Smith, AS Greenberg… - Biology of sex …, 2012 - Springer
Women have more body fat than men, but in contrast to the deleterious metabolic
consequences of the central obesity typical of men, the pear-shaped body fat distribution of …

Sex-specific differences in lipid and glucose metabolism

O Varlamov, CL Bethea, CT Roberts Jr - Frontiers in endocrinology, 2015 - frontiersin.org
Energy metabolism in humans is tuned to distinct sex-specific functions that potentially
reflect the unique requirements in females for gestation and lactation, whereas male …

Heterogeneity of white adipose tissue: molecular basis and clinical implications

KHM Kwok, KSL Lam, A Xu - Experimental & molecular medicine, 2016 - nature.com
Adipose tissue is a highly heterogeneous endocrine organ. The heterogeneity among
different anatomical depots stems from their intrinsic differences in cellular and physiological …

Adipose tissue heterogeneity: implication of depot differences in adipose tissue for obesity complications

MJ Lee, Y Wu, SK Fried - Molecular aspects of medicine, 2013 - Elsevier
Obesity, defined as excess fat mass, increases risks for multiple metabolic diseases, such as
type 2 diabetes, cardiovascular disease and several types of cancer. Over and above fat …

Adipose tissue inflammation and cardiovascular disease: an update

MN Rana, IJ Neeland - Current diabetes reports, 2022 - Springer
Abstract Purpose of Review The obesity epidemic is on the rise, and while it is well known
that obesity is associated with an increase in cardiovascular risk factors such as type 2 …

Role of body fat distribution and the metabolic complications of obesity

MD Jensen - The Journal of Clinical Endocrinology & …, 2008 - academic.oup.com
Context An upper body/visceral fat distribution in obesity is closely linked with metabolic
complications, whereas increased lower body fat is independently predictive of reduced …

[HTML][HTML] Sex dimorphism and depot differences in adipose tissue function

UA White, YD Tchoukalova - … et Biophysica Acta (BBA)-Molecular Basis of …, 2014 - Elsevier
Obesity, characterized by excessive adiposity, is a risk factor for many metabolic
pathologies, such as type 2 diabetes mellitus (T2DM). Numerous studies have shown that …