How the fetus withstands an environment of reduced oxygenation during life in the womb
has been a vibrant area of research since this field was introduced by Joseph Barcroft, a …

Acute neonatal encephalopathy remains a significant cause of death and long-term
disability. 1 Despite the highly adverse outcomes of moderate to severe encephalopathy …

Background Doppler studies of the fetal circulation in intrauterine growth retardation and
hypoxia have demonstrated a compensatory redistribution of arterial blood flow with …

A distinctive pattern of recurrent rapid falls in fetal heart rate, called decelerations, are
commonly associated with uterine contractions during labour. These brief decelerations are …

Studies in the research laboratory have demonstrated the complex relationship between
fetal and newborn asphyxia and brain damage, a balance between the degree, duration and …

One of the most distinctive features of fetal heart rate recordings in labor is the deceleration.
In clinical practice, there has been much confusion about the types of decelerations and …

Key points The in vivo fetal cardiovascular defence to chronic hypoxia has remained by and
large an enigma because no technology has been available to induce significant and …

The fetus mounts a coordinated cardiovascular response to an insult of acute hypoxaemia
which involves neural and endocrine components. During acute hypoxaemia in late …

We tested the hypothesis that fetal cardiovascular responses to hypoxemia change close to
full term in relation to the prepartum increase in fetal basal cortisol and investigated, in vivo …

Placental insufficiency resulting in restriction of fetal substrate supply and fetal hypoxaemia
is a major cause of restricted fetal growth and increased neonatal morbidity. Fetal …