Vascular remodeling, defined as any enduring change in the size and/or composition of an
adult blood vessel, allows adaptation and repair. On the other hand, inappropriate …

Atherothrombosis is a complex disease in which cholesterol deposition, inflammation, and
thrombus formation play a major role. Rupture of high-risk, vulnerable plaques is …

Objectives: We sought to determine the predictive ability of total white blood cell (WBC)
count and its subtypes for risk of death or myocardial infarction (MI). Background: An …

Objective: To summarize the structure, function, and regulation of matrix metalloproteinases
(MMPs) and to review the literature to date on their potential role in the pathogenesis of …

Pathologists have recognized arterial calcification for over a century. Recent years have
witnessed a strong resurgence of interest in atherosclerotic plaque calcification because it …

Despite all the advances of modern medicine, atherosclerosis continues to be one of the
most important medical and social problems. Atherosclerosis is the cause of several …

Despite the many studies of murine atherosclerosis, we do not yet know the relevance of the
natural history of this model to the final events precipitated by plaque disruption of human …

Background—The metabolic syndrome, which is characterized by a constellation of fasting
hyperglycemia, hypertriglyceridemia, low HDL cholesterol, hypertension, and/or abdominal …

Background—Matrix metalloproteinases (MMPs) are thought to play a prominent role in
atherogenesis and destabilization of plaque. Pericellularly localized membrane-type (MT) …

Background and aims In one-third of patients with acute coronary syndrome (ACS),
thrombosis occurs despite an intact fibrous cap (IFC)(IFC–ACS,'plaque erosion'). Recent …