In the moonlight: non-catalytic functions of ubiquitin and ubiquitin-like proteases

M Campos Alonso, KP Knobeloch - Frontiers in Molecular …, 2024 - frontiersin.org
Proteases that cleave ubiquitin or ubiquitin-like proteins (UBLs) are critical players in
maintaining the homeostasis of the organism. Concordantly, their dysregulation has been …

Collateral beauty in the damages: an overview of cosmetics and therapeutic applications of microbial proteases

SS Mousavi Ghahfarrokhi, FS Mahdigholi… - Archives of …, 2023 - Springer
Microbial proteases are enzymes secreted by a variety of microorganisms, including
bacteria and fungi, and have attracted significant attention due to their versatile applications …

Identification of novel toxins associated with the extracellular contractile injection system using machine learning

A Danov, I Pollin, E Moon, M Ho, BA Wilson… - Molecular Systems …, 2024 - embopress.org
Secretion systems play a crucial role in microbe-microbe or host-microbe interactions.
Among these systems, the extracellular contractile injection system (eCIS) is a unique …

Origin and early diversification of the papain family of cysteine peptidases

D Kordiš, V Turk - International Journal of Molecular Sciences, 2023 - mdpi.com
Peptidases of the papain family play a key role in protein degradation, regulated proteolysis,
and the host–pathogen arms race. Although the papain family has been the subject of many …

Elucidating the molecular properties and anti-mycobacterial activity of cysteine peptidase domain of D29 mycobacteriophage endolysin

R Gangakhedkar, V Jain - Journal of Virology, 2024 - journals.asm.org
Emergence of antibiotic resistance in pathogenic Mycobacterium tuberculosis (Mtb) has
elevated tuberculosis to a serious global threat, necessitating alternate solutions for its …

Genetic evidence for a regulated cysteine protease catalytic triad in LegA7, a Legionella pneumophila protein that impinges on a stress response pathway

D Hershkovitz, EJ Chen, AW Ensminger, AS Dugan… - mSphere, 2024 - journals.asm.org
Legionella pneumophila grows within membrane-bound vacuoles in phylogenetically
diverse hosts. Intracellular growth requires the function of the Icm/Dot type-IVb secretion …

Females translate male mRNA transferred during mating

LM Matzkin, JM Bono, HK Pigage, CW Allan, F Diaz… - Iscience, 2024 - cell.com
Although RNA is found in the seminal fluid of diverse organisms, it is unknown whether it is
functional within females. We developed a proteomic method (VESPA, Variant Enabled …

Processing of the Hepatitis E virus ORF1 nonstructural polyprotein

YA Karpe - Frontiers in Virology, 2024 - frontiersin.org
Hepatitis E viruses (HEV) Open Reading Frame 1 (ORF1) encodes a non-structural
polyprotein. In most positive-sense RNA viruses found in animals, this non-structural …

Papain assisted preparation of chitosan: Feasibility study for candidate in-house reference material and antibacterial agent

RB Istiningrum, I Puspasari, AR Wijaya, H Hidayat - Food and Humanity, 2024 - Elsevier
Chitosan preparation assisted by papain was carried out to reduce the use of chemicals in
the extraction of chitosan. This research aims to modify the chitosan extraction method to be …

Evaluación del efecto antifúngico del lactosuero sobre Penicillium sp. en arepas de maíz y yuca

LF Navarrete Osorio - repositorio.unal.edu.co
Las arepas son productos que se obtienen a partir de la masa de maíz blanca, amarilla o
mezcla de ambas previamente cocida, mezclada con otros ingredientes como sal, queso …