Since cancer stem cells (CSCs) were first identified in leukemia in 1994, they have been
considered promising therapeutic targets for cancer therapy. These cells have self-renewal …

Lung cancer causes the largest number of cancer-related deaths in the world. Most (85%) of
lung cancers are classified as non-small-cell lung cancer (NSCLC) and small-cell lung …

Developing biomimetic nanoparticles without loss of the integrity of proteins remains a major
challenge in cancer chemotherapy. Here, we develop a biocompatible tumor-cell …

The lineage transition between epithelium and mesenchyme is a process known as
epithelial–mesenchymal transition (EMT), by which polarized epithelial cells lose their …

The efficacy of chemotherapy is one of the main challenges in cancer treatment and one of
the major obstacles to overcome in achieving lasting remission and a definitive cure in …

Cancer metastasis and therapy resistance are the major unsolved clinical challenges, and
account for nearly all cancer-related deaths. Both metastasis and therapy resistance are …

Since their identification in 1994, cancer stem cells (CSCs) have been objects of intensive
study. Their properties and mechanisms of formation have become a major focus of current …

The cancer stem cell (CSC) hypothesis has captured the attention of many scientists. It is
believed that elimination of CSCs could possibly eradicate the whole cancer. CSC surface …

Cancer stem cells (CSCs) have been identified as rare cell populations in many cancers,
including leukemia and solid tumors. Accumulating evidence has suggested that CSCs are …

Simple Summary Cancer is one of the hardest pathologies to fight, being one of the main
causes of death worldwide despite the constant development of novel therapeutic strategies …