As a promising alternative platform for cellular immunotherapy, natural killer cells (NK) have
recently gained attention as an important type of innate immune regulatory cell. NK cells can …

Simple Summary Despite an initial response to therapy, many lung cancer patients
inevitably develop resistance to therapy leading to decreased duration of response and …

The complex orchestration of gene expression that mediates the transition of epithelial cells
into mesenchymal cells is implicated in cancer development and metastasis. As the primary …

Gastric cancer (GC) is one of the most common malignant tumors of digestive systems
worldwide, with high recurrence and mortality. Chemotherapy is still the standard treatment …

Introduction: Paclitaxel is a microtubule stabilizer that is currently one of the most utilized
chemotherapeutic agents. Its efficacy in breast, uterine, lung and other neoplasms made its …

Background: Platinum-based chemotherapy, cisplatin (DDP) specifically, is the main
strategy for treating lung cancer (LC). However, currently, there is a lack of predictive drug …

Nonsmall cell lung cancer (NSCLC) is highly malignant with limited treatment options,
platinum-based chemotherapy is a standard treatment for NSCLC with resistance commonly …

Resolution to chemoresistance is a major challenge in patients with advanced-stage
malignancies. Thus, identification of action points and elucidation of molecular mechanisms …

Lung cancer has been the leading cause of cancer-related deaths worldwide for decades.
Despite the increasing understanding of the underlying disease mechanisms, the prognosis …

Simple Summary Cancer remains a major killer of the human population. Current cancer
diagnostic and therapeutic methods are associated with shortcomings of limited targetability …