Adjuvants are indispensable components of vaccines for stimulating optimal immune
responses to non-replicating, inactivated and subunit antigens. Eliciting balanced humoral …

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. As a
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …

Antigen-specific, MHC-restricted αβ T cells are necessary for protective immunity against
Mycobacterium tuberculosis, but the ability to broadly study these responses has been …

Given the encouraging clinical results of both candidate subunit vaccines and revaccination
with Bacillus Calmette-Guérin (BCG) against tuberculosis (TB), there is support for …

Tuberculosis (TB), caused by Mycobacterium tuberculosis is the world's deadliest bacterial
infection, resulting in more than 1.4 million deaths annually. The emergence of drug …

Background Tuberculosis is a major public health problem worldwide. Immunisation with
Mycobacterium bovis BCG vaccine is partially effective in infants, reducing the incidence of …

CD4 T cells are essential for immunity to tuberculosis because they produce cytokines,
including interferon-γ. Whether CD4 T cells act as" helper" cells to promote optimal CD8 T …

Vaccine development against tuberculosis (TB) is based on the induction of adaptive
immune responses endowed with long-term memory against mycobacterial antigens …

The year 2020 was shaped by the COVID-19 pandemic which killed more people than any
other infectious disease in this particular year. At the same time, the development of highly …

Tuberculosis is the leading infectious disease killer globally due to a single pathogen.
Despite wide deployment of standard drug regimens, modern diagnostics and a vaccine …