Biomaterials for chimeric antigen receptor T cell engineering
H Niu, P Zhao, W Sun - Acta Biomaterialia, 2023 - Elsevier
Chimeric antigen receptor T (CAR-T) cells have achieved breakthrough efficacies against
hematological malignancies, but their unsatisfactory efficacies in solid tumors limit their …
hematological malignancies, but their unsatisfactory efficacies in solid tumors limit their …
In vivo mRNA delivery to virus-specific T cells by light-induced ligand exchange of MHC class I antigen-presenting nanoparticles
Simultaneous delivery of mRNA to multiple populations of antigen (Ag)–specific CD8+ T
cells is challenging given the diversity of peptide epitopes and polymorphism of class I major …
cells is challenging given the diversity of peptide epitopes and polymorphism of class I major …
In vivo gene delivery to immune cells
Highlights•Immune cell therapies are a new class of treatments for complex human
diseases.•Engineering immune cells in vivo can improve manufacturing, efficacy, and …
diseases.•Engineering immune cells in vivo can improve manufacturing, efficacy, and …
Implantable CAR T cell factories enhance solid tumor treatment
Abstract Chimeric Antigen Receptor (CAR) T cell therapy has produced revolutionary
success in hematological cancers such as leukemia and lymphoma. Nonetheless, its …
success in hematological cancers such as leukemia and lymphoma. Nonetheless, its …
Selenium nanoparticles enhance mucosal immunity against Mycobacterium bovis infection
X Ge, Z Liang, K Li, Y Dong, Y Wang, Y Liu… - International …, 2024 - Elsevier
Selenium nanoparticles (SeNPs) enhance the immune response as adjuvants, increasing
the efficacy of viral vaccines, including those for COVID-19. However, the efficiency of …
the efficacy of viral vaccines, including those for COVID-19. However, the efficiency of …