Designed Nanomaterials‐Assisted Proteomics and Metabolomics Analysis for In Vitro Diagnosis

Y Wang, R Li, W Shu, X Chen, Y Lin, J Wan - Small Methods, 2024 - Wiley Online Library
In vitro diagnosis (IVD) is pivotal in modern medicine, enabling early disease detection and
treatment optimization. Omics technologies, particularly proteomics and metabolomics, offer …

Applications of Raman spectroscopy in clinical medicine

Y Qi, EX Chen, D Hu, Y Yang, Z Wu, M Zheng… - Food …, 2024 - Wiley Online Library
Raman spectroscopy is a nondestructive and highly effective technique for analyzing
biological tissues and diagnosing diseases by providing detailed spectral information about …

[HTML][HTML] Role of precision medicine and personalized medicine in the treatment of diseases

M Farrokhi, F Taheri, PJ Khouzani, E Rahmani… - Kindle, 2023 - preferpub.org
Precision medicine and personalized medicine are two approaches to healthcare that aim to
tailor medical treatments and interventions to individual patients. These approaches are …

Monitoring metabolic changes in response to chemotherapies in cancer with Raman spectroscopy and metabolomics

G Cutshaw, N Hassan, S Uthaman, X Wen… - Analytical …, 2023 - ACS Publications
Resistance to clinical therapies remains a major barrier in cancer management. There is a
critical need for rapid and highly sensitive diagnostic tools that enable early prediction of …

RSPSSL: A novel high-fidelity Raman spectral preprocessing scheme to enhance biomedical applications and chemical resolution visualization

J Hu, GJ Chen, C Xue, P Liang, Y Xiang… - Light: Science & …, 2024 - nature.com
Raman spectroscopy has tremendous potential for material analysis with its molecular
fingerprinting capability in many branches of science and technology. It is also an emerging …

Label-Free Multiplex Profiling of Exosomal Proteins with a Deep Learning-Driven 3D Surround-Enhancing SERS Platform for Early Cancer Diagnosis

M Chen, H Wang, Y Zhang, H Jiang, T Li, L Liu… - Analytical …, 2024 - ACS Publications
Identification of protein profiling on plasma exosomes by SERS can be a promising strategy
for early cancer diagnosis. However, it is still challenging to detect multiple exosomal …

A database of computed Raman spectra of inorganic compounds with accurate hybrid functionals

Y Li, DKJ Lee, P Cai, Z Zhang, P Gorai, P Canepa - Scientific Data, 2024 - nature.com
Raman spectroscopy is widely applied in identifying local structures in materials, but the
interpretation of Raman spectra is non-trivial. An accurate computational database of …

Metabolism changes caused by glucose in normal and cancer human brain cell lines by Raman imaging and chemometric methods

M Kopec, K Beton-Mysur, J Surmacki, H Abramczyk - Scientific Reports, 2024 - nature.com
Glucose is the main source of energy for the human brain. This paper presents a non-
invasive technique to study metabolic changes caused by glucose in human brain cell lines …

Predicting the onset of preeclampsia by longitudinal monitoring of metabolic changes throughout pregnancy with Raman spectroscopy

S Ghazvini, S Uthaman, L Synan, EC Lin… - Bioengineering & …, 2024 - Wiley Online Library
Preeclampsia is a life‐threatening pregnancy disorder. Current clinical assays cannot
predict the onset of preeclampsia until the late 2nd trimester, which often leads to poor …

A Systematic Approach toward Enabling Maximal Targeting Efficiency of Cell Surface Proteins with Actively Targeted SERS Nanoparticles

P Bagheri, OE Eremina, A Fernando… - … Applied Materials & …, 2024 - ACS Publications
With their intricate design, nanoparticles (NPs) have become indispensable tools in the
quest for precise cellular targeting. Among various NPs, gold NPs stand out with unique …