Furanone, a five-membered heteroaromatic ring containing oxygen atom, is of immense
pharmaceutical importance. Presence of this nucleus in biologically active compounds of …

Abstract A series of (E)-N-2 (5H)-furanonyl sulfonyl hydrazone derivatives have been
rationally designed and efficiently synthesized by one-pot reaction with good yields for the …

Cancer is currently one of the foremost health challenges and a leading cause of death
worldwide. Cervical cancer is caused by cofactors, including oral contraceptive use …

Organic thioethers play an important role in the discovery of drugs and natural products.
However, the green synthesis of organic sulfide compounds remains a challenging task. The …

This review aims to highlight the role of silicon in drug discovery. Silicon and carbon are
often regarded as being similar with silicon located directly beneath carbon in the same …

Electronic cigarette (e-cig) usage has risen dramatically worldwide over the past decade.
While they are touted as a safe alternative to cigarettes, recent studies indicate that high …

For the first time, eight novel artemisinin-piperazine-furane ether hybrids (5a− h) were
efficiently synthesized and investigated for their in vitro cytotoxic activity against some …

This work pioneers the thermocatalytic conversion of tagua seeds (or ivory nut) from the
palm Phytelephas aequatorialis into key chemical building blocks, being levoglucosenone …

In the quest to discover novel scaffolds with leishmanicidal effects, a series of 23 compounds
containing the most promising 1, 2, 3-triazole and highly potent butenolide in one framework …

The pharmacological effects of carbon to silicon bioisosteric replacements have been widely
explored in drug design and medicinal chemistry. Here, we present a systematic …