Bacterial, protozoan and other microbial infections share an accelerated metabolic rate. In
order to ensure a proper functioning of cell replication and proteins and nucleic acids …

Nearly 30 years after the advent of antiretroviral therapy (ART), CNS opportunistic infections
remain a major cause of morbidity and mortality in HIV-positive individuals. Unknown HIV …

It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

The human immunodeficiency virus-1 (HIV-1) enters target cells by binding its envelope
glycoprotein gp120 to the CD4 receptor and/or coreceptors such as CC chemokine receptor …

KELSO ET AL 27 allergy. Only for patients with a history of allergic reaction to influenza
vaccine itself is additional evaluation appropriate, including skin testing with the vaccine and …

Ultra-long-acting integrase strand transfer inhibitors were created by screening a library of
monomeric and dimeric dolutegravir (DTG) prodrug nanoformulations. This led to an 18 …

More than 360 million persons worldwide (6% of the world population) are chronically
infected by the hepatitis B virus (HBV). Although the incidence of HBV infection has …

Hepatitis C virus (HCV) is an RNA virus that affects> 180 million individuals worldwide with a
high propensity for chronic infection. Children with HCV infection differ from adults in several …

Tuberculous meningitis (TBM) is the most common form of central nervous system
tuberculosis (TB) and has very high morbidity and mortality. TBM is typically a subacute …

We performed a search using MEDLINE (1950 to August 2011) and Embase (1980 to 2011),
along with a manual review of relevant bibliographies. We used the permuted index search …