Colchicine is an ancient medication that is currently approved for the treatment of gout and
FMF. However, colchicine has a wide range of anti-inflammatory activities, and studies …

Colchicine and statins are frequently co‐prescribed for prevention and treatment of
cardiovascular diseases, auto‐inflammatory diseases, and gout. Both are substrates and …

Introduction: Statins remain among the most frequently prescribed drugs and constitute a
cornerstone in the prevention of cardiovascular disease. However, muscle symptoms are …

Purpose Disease management of stable coronary artery disease consists of controlling
hemostasis and lipid regulation. No treatment strategies preventing plaque erosion or …

Colchicine is a medication most commonly used in the treatment of gout and familial
mediterannean fever. A rare complication of therapy is toxicity causing proximal myopathy …

During the first months after the initiation of urate-lowering therapy in gout patients, the risk
of exacerbation of arthritis considerably rises, which often results in discontinuation of the …

Statins and colchicine co-administration consists of a potentially catastrophic drug–drug
interaction since it provokes myotoxicity, myopathy and various degrees of rhabdomyolysis …

An 80-year-old patient with diabetes mellitus, chronic bronchitis, and chronic heart failure
presented with pain in the right calf after one dose of atorvastatin. Significant increases in …

A 74-year-old man with medical history significant for atrial fibrillation, hyperlipidaemia and
coronary artery disease on atorvastatin presented to the emergency department with …

Introdução: Dentre os sintomas musculares associados às estatinas (SMAE), a rabdomiólise
é, frequentemente, a manifestação de pior prognóstico. Apesar de ser considerada rara …