Immunogenic cell death activates the tumor immune microenvironment to boost the immunotherapy efficiency
Z Li, X Lai, S Fu, L Ren, H Cai, H Zhang, Z Gu… - Advanced …, 2022 - Wiley Online Library
Tumor immunotherapy is only effective in a fraction of patients due to a low response rate
and severe side effects, and these challenges of immunotherapy in clinics can be addressed …
and severe side effects, and these challenges of immunotherapy in clinics can be addressed …
Translational applications of hydrogels
Advances in hydrogel technology have unlocked unique and valuable capabilities that are
being applied to a diverse set of translational applications. Hydrogels perform functions …
being applied to a diverse set of translational applications. Hydrogels perform functions …
[HTML][HTML] Turning cold tumors into hot tumors by improving T-cell infiltration
YT Liu, ZJ Sun - Theranostics, 2021 - ncbi.nlm.nih.gov
Immunotherapy, represented by immune checkpoint inhibitors (ICIs), has greatly improved
the clinical efficacy of malignant tumor therapy. ICI-mediated antitumor responses depend …
the clinical efficacy of malignant tumor therapy. ICI-mediated antitumor responses depend …
Metallo-alginate hydrogel can potentiate microwave tumor ablation for synergistic cancer treatment
Microwave ablation (MWA) as a local tumor ablation strategy suffers from posttreatment
tumor recurrence. Development of adjuvant biomaterials to potentiate MWA is therefore of …
tumor recurrence. Development of adjuvant biomaterials to potentiate MWA is therefore of …
Activatable polymer nanoagonist for second near-infrared photothermal immunotherapy of cancer
Nanomedicine in combination with immunotherapy offers opportunities to treat cancer in a
safe and effective manner; however, remote control of immune response with spatiotemporal …
safe and effective manner; however, remote control of immune response with spatiotemporal …
[HTML][HTML] A tumor cell membrane-coated self-amplified nanosystem as a nanovaccine to boost the therapeutic effect of anti-PD-L1 antibody
To improve the response rate of immune checkpoint inhibitors such as anti-PD-L1 antibody
in immunosuppressive cancers like triple-negative breast cancer (TNBC), induction of …
in immunosuppressive cancers like triple-negative breast cancer (TNBC), induction of …
Biomineralized two‐enzyme nanoparticles regulate tumor glycometabolism inducing tumor cell pyroptosis and robust antitumor immunotherapy
S Zhang, Y Zhang, Y Feng, J Wu, Y Hu, L Lin… - Advanced …, 2022 - Wiley Online Library
Currently, immune checkpoint therapy combined with chemotherapy and radiotherapy is a
useful strategy for improving immunotherapy's therapeutic efficacy. However, chemotherapy …
useful strategy for improving immunotherapy's therapeutic efficacy. However, chemotherapy …
A nitric-oxide driven chemotactic nanomotor for enhanced immunotherapy of glioblastoma
H Chen, T Li, Z Liu, S Tang, J Tong, Y Tao… - Nature …, 2023 - nature.com
The major challenges of immunotherapy for glioblastoma are that drugs cannot target tumor
sites accurately and properly activate complex immune responses. Herein, we design and …
sites accurately and properly activate complex immune responses. Herein, we design and …
Amplification of activated near-infrared afterglow luminescence by introducing twisted molecular geometry for understanding neutrophil-involved diseases
Understanding the mechanism and progression of neutrophil-involved diseases (eg, acute
inflammation) is of great importance. However, current available analytical methods neither …
inflammation) is of great importance. However, current available analytical methods neither …
Engineered nanoparticles for cancer vaccination and immunotherapy
Conspectus The immune system has evolved over time to protect the host from foreign
microorganisms. Activation of the immune system is predicated on a distinction between self …
microorganisms. Activation of the immune system is predicated on a distinction between self …