Recombinant human lactoferrin: a valuable protein for pharmaceutical products and functional foods
Lactoferrin, the main iron-binding protein of milk, has biological activities that are essential
for the newborn and are beneficial for adults. Given this beneficial effect, there is broad …
for the newborn and are beneficial for adults. Given this beneficial effect, there is broad …
Cattle mammary bioreactor generated by a novel procedure of transgenic cloning for large-scale production of functional human lactoferrin
Large-scale production of biopharmaceuticals by current bioreactor techniques is limited by
low transgenic efficiency and low expression of foreign proteins. In general, a bacterial …
low transgenic efficiency and low expression of foreign proteins. In general, a bacterial …
[HTML][HTML] Expression and bioactivity of recombinant human lysozyme in the milk of transgenic mice
Z Yu, Q Meng, H Yu, B Fan, S Yu, J Fei, L Wang… - Journal of dairy …, 2006 - Elsevier
Human milk lysozyme is an important protein for innate immunity, but human breast milk is a
fairly poor source for commercial production of this enzyme. Research on the expression of …
fairly poor source for commercial production of this enzyme. Research on the expression of …
Production of transgenic-cloned pigs expressing large quantities of recombinant human lysozyme in milk
D Lu, S Liu, S Shang, F Wu, X Wen, Z Li, Y Li, X Hu… - PloS one, 2015 - journals.plos.org
Human lysozyme is a natural non-specific immune factor in human milk that plays an
important role in the defense of breastfed infants against pathogen infection. Although …
important role in the defense of breastfed infants against pathogen infection. Although …
High-level expression of bioactive recombinant human lysozyme in the milk of transgenic mice using a modified human lactoferrin BAC
S Liu, X Li, D Lu, S Shang, M Wang, M Zheng… - Transgenic …, 2012 - Springer
Transgenesis has been used for expressing human lysozyme (hLZ) in the milk of livestock to
improve their disease resistance. Here we describe a human lactoferrin (hLF) BAC as a …
improve their disease resistance. Here we describe a human lactoferrin (hLF) BAC as a …
Hybrid expression cassettes consisting of a milk protein promoter and a cytomegalovirus enhancer significantly increase mammary‐specific expression of human …
Y Cheng, L An, YG Yuan, Y Wang… - Molecular …, 2012 - Wiley Online Library
It is very important to develop an effective, specific, and robust expression cassette that
ensures a high level of expression in the mammary glands. In this study, we designed and …
ensures a high level of expression in the mammary glands. In this study, we designed and …
Expression of Recombinant Human Alpha‐Lactalbumin in the Milk of Transgenic Goats Using a Hybrid Pomoter/Enhancer
YG Yuan, L An, B Yu, S Song, F Zhou… - Journal of Analytical …, 2014 - Wiley Online Library
To improve nutrient content of goat milk, we describe the construction of a vector (pBLAC)
containing a hybrid goat β‐lactoglobulin (BLG) promoter/cytomegalovirus (CMV) enhancer …
containing a hybrid goat β‐lactoglobulin (BLG) promoter/cytomegalovirus (CMV) enhancer …
[PDF][PDF] 人乳铁蛋白转基因研究进展
赵春江, 刘兆良, 樊宝良, 李宁 - 农业生物技术学报, 2004 - journal05.magtech.org.cn
人乳铁蛋白是一种具有多种生理功能的糖基化蛋白, 可可逆性地结合两个铁离子.
概述了人乳铁蛋白的结构和理化性质, 以及乳铁蛋白基因的结构, 并着重论述了人乳铁蛋白 …
概述了人乳铁蛋白的结构和理化性质, 以及乳铁蛋白基因的结构, 并着重论述了人乳铁蛋白 …
High-level expression and production of human lactoferrin in
T Jiang, L Chen, S Jia, L Chen, Y Ma - Dairy Science and …, 2008 - dairy-journal.org
Lactoferrin (LF) is a multifunctional iron-binding glycoprotein which is found in high
concentrations in milk. Recombinant human LF (rhLF) may provide health benefits. In the …
concentrations in milk. Recombinant human LF (rhLF) may provide health benefits. In the …
Molecular-based environmental risk assessment of three varieties of genetically engineered cows
J Xu, J Zhao, J Wang, Y Zhao, L Zhang, M Chu, N Li - Transgenic research, 2011 - Springer
The development of animal biotechnology has led to an increase in attention to biosafety
issues. Here we evaluated the impact of genetically engineered cows on the environment …
issues. Here we evaluated the impact of genetically engineered cows on the environment …