Vitamin B12, folate, and the methionine remethylation cycle—biochemistry, pathways, and regulation

DS Froese, B Fowler… - Journal of inherited …, 2019 - Wiley Online Library
Abstract Vitamin B12 (cobalamin, Cbl) is a nutrient essential to human health. Due to its
complex structure and dual cofactor forms, Cbl undergoes a complicated series of …

[HTML][HTML] Classic highlights in porphyrin and porphyrinoid total synthesis and biosynthesis

MO Senge, NN Sergeeva, KJ Hale - Chemical Society Reviews, 2021 - pubs.rsc.org
Porphyrins feature prominently in nature, be it as enzymatic cofactors, electron and exciton
shuffles, as photoactive dyes, or as signaling substances. Their involvement in the …

Functional roles of B‐vitamins in the gut and gut microbiome

T Uebanso, T Shimohata, K Mawatari… - Molecular nutrition & …, 2020 - Wiley Online Library
The gut microbiota produce hundreds of bioactive compounds, including B‐vitamins, which
play significant physiological roles in hosts by supporting the fitness of symbiotic species …

[HTML][HTML] Gut microbiota profiling: metabolomics based approach to unravel compounds affecting human health

P Vernocchi, F Del Chierico, L Putignani - Frontiers in microbiology, 2016 - frontiersin.org
The gut microbiota is composed of a huge number of different bacteria, that produce a large
amount of compounds playing a key role in microbe selection and in the construction of a …

Bacteria as vitamin suppliers to their host: a gut microbiota perspective

JG LeBlanc, C Milani, GS De Giori, F Sesma… - Current opinion in …, 2013 - Elsevier
Food-related lactic acid bacteria (LAB) as well as human gut commensals such as
bifidobacteria can de novo synthesize and supply vitamins. This is important since humans …

Biosynthesis of the modified tetrapyrroles—the pigments of life

DA Bryant, CN Hunter, MJ Warren - Journal of Biological Chemistry, 2020 - ASBMB
Modified tetrapyrroles are large macrocyclic compounds, consisting of diverse conjugation
and metal chelation systems and imparting an array of colors to the biological structures that …

[HTML][HTML] Functions of elements in soil microorganisms

M Hemkemeyer, SA Schwalb, S Heinze… - Microbiological …, 2021 - Elsevier
The soil microbial community fulfils various functions, such as nutrient cycling and carbon
(C) sequestration, therefore contributing to maintenance of soil fertility and mitigation of …

Chromatin state dynamics during blood formation

D Lara-Astiaso, A Weiner, E Lorenzo-Vivas, I Zaretsky… - science, 2014 - science.org
Chromatin modifications are crucial for development, yet little is known about their dynamics
during differentiation. Hematopoiesis provides a well-defined model to study chromatin state …

[PDF][PDF] Vitamin B12 as a modulator of gut microbial ecology

PH Degnan, ME Taga, AL Goodman - Cell metabolism, 2014 - cell.com
The microbial mechanisms and key metabolites that shape the composition of the human
gut microbiota are largely unknown, impeding efforts to manipulate dysbiotic microbial …

Vitamin B12 status in health and disease: a critical review. Diagnosis of deficiency and insufficiency – clinical and laboratory pitfalls

A Sobczyńska-Malefora, E Delvin… - Critical reviews in …, 2021 - Taylor & Francis
Vitamin B12 (cobalamin) is an essential cofactor for two metabolic pathways. It is obtained
principally from food of animal origin. Cobalamin becomes bioavailable through a series of …