Corticosteroids have numerous applications in treating inflammation and diseases of
immune function based on their significant anti-inflammatory and immunosuppressive …

Aerosolised drugs are prescribed for use in a range of inhaler devices and systems.
Delivering drugs by inhalation requires a formulation that can be successfully aerosolised …

BACKGROUND: Measurement of biomarkers has been incorporated within clinical research
studies of asthma to characterize the population and associate the disease with …

BACKGROUND: The goals of asthma treatment include preventing recurrent exacerbations.
Yet there is no consensus about the terminology for describing or defining “exacerbation” or …

Research in the area of pulmonary drug delivery has gathered momentum in the last several
years, with increased interest in using the lung as a means of delivering drugs systemically …

Background: A clinical model is needed to compare inhaled corticosteroids (ICSs) with
respect to efficacy. Objective: The purpose of this investigation was to compare the relative …

Rationale: One-quarter to one-third of individuals with asthma smoke, which may affect
response to therapy and contribute to poor asthma control. Objectives: To determine if the …

Extensive development of inhaled and oral glucocorticoids has resulted in highly potent
molecules that have been optimized to target activity to the lung and minimize systemic …

Asthma is a complex disease of the respiratory tract associated with chronic inflammation in
which an intricate network of cells and cellular factors plays a major role. Asthma is one of …

Obstructive sleep apnea (OSA) and asthma are highly prevalent chronic respiratory
disorders. Beyond their frequent coexistence arising from their high prevalence and shared …