Diabetic foot ulcers (DFUs) are a serious complication of diabetes that results in significant
morbidity and mortality. Mortality rates associated with the development of a DFU are …

Cutaneous wound healing in adult mammals is a complex multi-step process involving
overlapping stages of blood clot formation, inflammation, re-epithelialization, granulation …

Nowadays, there has been an increase in the number of people with chronic wounds, which
has resulted in serious health problems worldwide. The rate-limiting stage of chronic wound …

The healing of diabetic foot ulcers (DFUs) is a major challenge for clinical treatment because
of the hyperglycemic and acidic microenvironment in the wound area. In this study, a self …

Wound healing is a complex physiological process that occurs in the human body involving
the sequential activation of multiple cell types and signaling pathways in a coordinated …

Chitosan-based nanofibers (CS-NFs) are excellent artificial extracellular matrices (ECMs)
due to the resemblance of CS with the glycosaminoglycans of the natural ECMs. Despite this …

Diabetes skin infection is a very common disorder in hyperglycemic patients. This study
evaluated the prospective of developing a topical gel formulation of Aloe vera with insulin …

Wound healing is a complex biological process that repairs damaged tissues and restores
skin integrity. Insulin, a potent factor of wound healing, has been reported for nearly a …

Due to the poor ability of self-repair and regeneration, articular cartilage and subchondral
bone defects and degradation are still a big problem nowadays. The aim of the present …

Effective therapy of wounds is difficult, especially for chronic, non-healing wounds, and
novel therapeutics are urgently needed. This challenge can be addressed with bioactive …