[HTML][HTML] Gradual adaptation of animal influenza a viruses to human-type sialic acid receptors

M Liu, FJM van Kuppeveld, CAM de Haan… - Current Opinion in …, 2023 - Elsevier
Influenza A viruses (IAVs) originating from animal reservoirs pose continuous threats to
human health as demonstrated by the Spanish flu pandemic. Infection starts by attachment …

Vaccination and antiviral treatment against Avian influenza H5Nx viruses: a harbinger of virus control or evolution

A Alasiri, R Soltane, A Hegazy, AM Khalil… - Vaccines, 2023 - mdpi.com
Despite the panzootic nature of emergent highly pathogenic avian influenza H5Nx viruses in
wild migratory birds and domestic poultry, only a limited number of human infections with …

Dominant subtype switch in avian influenza viruses during 2016–2019 in China

Y Bi, J Li, S Li, G Fu, T Jin, C Zhang, Y Yang… - Nature …, 2020 - nature.com
We have surveyed avian influenza virus (AIV) genomes from live poultry markets within
China since 2014. Here we present a total of 16,091 samples that were collected from May …

The emergence of new antigen branches of H9N2 avian influenza virus in China due to antigenic drift on hemagglutinin through antibody escape at immunodominant …

N Zhang, K Quan, Z Chen, Q Hu, M Nie… - Emerging microbes & …, 2023 - Taylor & Francis
Vaccination is a crucial prevention and control measure against H9N2 avian influenza
viruses (AIVs) that threaten poultry production and public health. However, H9N2 AIVs in …

H5N1 infection impairs the alveolar epithelial barrier through intercellular junction proteins via Itch-mediated proteasomal degradation

T Ruan, Y Sun, J Zhang, J Sun, W Liu, RA Prinz… - Communications …, 2022 - nature.com
The H5N1 subtype of the avian influenza virus causes sporadic but fatal infections in
humans. H5N1 virus infection leads to the disruption of the alveolar epithelial barrier, a …

The evolution of highly pathogenic avian influenza A (H5) in poultry in Nigeria, 2021–2022

C Meseko, A Milani, B Inuwa, C Chinyere, I Shittu… - Viruses, 2023 - mdpi.com
In 2021, amidst the COVID-19 pandemic and global food insecurity, the Nigerian poultry
sector was exposed to the highly pathogenic avian influenza (HPAI) virus and its economic …

N-linked glycosylation enhances hemagglutinin stability in avian H5N6 influenza virus to promote adaptation in mammals

H Sun, G Deng, H Sun, J Song, W Zhang, H Li… - PNAS …, 2022 - academic.oup.com
Abstract Clade 2.3. 4.4 avian H5Ny viruses, namely H5N2, H5N6, and H5N8, have exhibited
unprecedented intercontinental spread in poultry. Among them, only H5N6 viruses are …

Adaptation of two wild bird-origin H3N8 avian influenza viruses to mammalian hosts

J Liang, Q Li, L Cai, Q Yuan, L Chen, Q Lin, C Xiao… - Viruses, 2022 - mdpi.com
Wild birds play an important role in the emergence, evolution, and spread of zoonotic avian
influenza viruses (AIVs). However, there are few studies on the cross-species transmission …

Epitopes in the HA and NA of H5 and H7 avian influenza viruses that are important for antigenic drift

JM Luczo, E Spackman - FEMS Microbiology Reviews, 2024 - academic.oup.com
Avian influenza viruses evolve antigenically to evade host immunity. Two influenza A virus
surface glycoproteins, the haemagglutinin and neuraminidase, are the major targets of host …

Avian influenza overview February–May 2018

European Food Safety Authority… - EFSA …, 2018 - Wiley Online Library
Between 16 February and 15 May 2018, three highly pathogenic avian influenza (HPAI) A
(H5N6) and 11 HPAI A (H5N8) outbreaks in poultry holdings, one HPAI A (H5N6) and one …