Adherence to single-pill versus free-equivalent combination therapy in hypertension: a systematic review and meta-analysis

G Parati, S Kjeldsen, A Coca, WC Cushman… - Hypertension, 2021 - Am Heart Assoc
Poor adherence to antihypertensive therapy is a major cause of poor blood pressure (BP)
control in patients with hypertension. Regimen simplification may improve adherence and …

Fixed dose drug combinations–are they pharmacoeconomically sound? Findings and implications especially for lower-and middle-income countries

B Godman, H McCabe, TD Leong… - Expert review of …, 2020 - Taylor & Francis
Introduction There are positive aspects regarding the prescribing of fixed dose combinations
(FDCs) versus prescribing the medicines separately. However, these have to be balanced …

[HTML][HTML] Impact of single-pill combination therapy on adherence, blood pressure control, and clinical outcomes: a rapid evidence assessment of recent literature

K Tsioufis, R Kreutz, G Sykara, J van Vugt… - Journal of …, 2020 - journals.lww.com
Objective: The 2018 European Society of Cardiology/European Society of Hypertension
Guidelines for the management of arterial hypertension raised the need for evidence to …

[HTML][HTML] Persistence as a robust indicator of medication adherence-related quality and performance

E Menditto, C Cahir, S Malo, I Aguilar-Palacio… - International journal of …, 2021 - mdpi.com
Medication adherence is a priority for health systems worldwide and is widely recognised as
a key component of quality of care for disease management. Adherence-related indicators …

Impact of single-pill combinations versus free-equivalent combinations on adherence and persistence in patients with hypertension and dyslipidemia: a systematic …

AP Kengne, JB Brière, P Le Nouveau… - Expert Review of …, 2024 - Taylor & Francis
Objectives Hypertension is a leading cause of death and disease burden followed by
dyslipidemia. Their asymptomatic nature leads to low adherence and persistence to …

[HTML][HTML] Effectiveness of perindopril/amlodipine fixed-dose combination in the treatment of hypertension: a systematic review

TV Dat, VL Tu, LNA Thu, NNA Quang, V Binh… - Frontiers in …, 2024 - frontiersin.org
Background: Uncontrolled blood pressure is a major risk factor for cardiovascular diseases.
Fixed-dose combination (FDC) therapy offers a promising approach to addressing this …

[HTML][HTML] A real-world analysis of outcomes and healthcare costs of patients on perindopril/indapamide/amlodipine single-pill vs. multiple-pill combination in Italy

JR Snyman, LA Bortolotto, L Degli Esposti… - Journal of …, 2024 - journals.lww.com
Objectives: This analysis compared adherence, cardiovascular (CV) events and all-cause
mortality incidence, and healthcare costs among hypertensive patients treated with …

[HTML][HTML] HIV treatment regimens and adherence to national guidelines in Australia: an analysis of dispensing data from the Australian pharmaceutical benefits scheme

NJ Dharan, T Radovich, S Che, K Petoumenos… - BMC Public Health, 2019 - Springer
Background Treatment guidelines for antiretroviral therapy (ART) have evolved to
emphasize newer regimens that address ageing-related comorbidities. Using national …

Fixed‐dose combination of amlodipine and atorvastatin improves clinical outcomes in patients with concomitant hypertension and dyslipidemia

CP Lin, YC Tung, FC Hsiao, CH Yang… - The Journal of …, 2020 - Wiley Online Library
Hypertension and dyslipidemia are important risk factors for cardiovascular disease.
However, the clinical outcomes of fixed‐dose combination (FDC) versus free‐equivalent …

Cost-effectiveness analysis comparing single-pill combination of perindopril/amlodipine/indapamide to the free equivalent combination in patients with hypertension …

P Levy, T Lemański, C Crossan… - Expert Review of …, 2024 - Taylor & Francis
Objective To evaluate the cost-effectiveness of a single-pill combination (SPC) of
perindopril/amlodipine/indapamide versus its free equivalent combination (FEC) in adults …