What is polypharmacy? A systematic review of definitions

N Masnoon, S Shakib, L Kalisch-Ellett, GE Caughey - BMC geriatrics, 2017 - Springer
Background Multimorbidity and the associated use of multiple medicines (polypharmacy), is
common in the older population. Despite this, there is no consensus definition for …

Functional versus chronological age: geriatric assessments to guide decision making in older patients with cancer

E Soto-Perez-de-Celis, D Li, Y Yuan, YM Lau… - The Lancet …, 2018 - thelancet.com
As the worldwide population ages, oncologists are often required to make difficult and
complex decisions regarding the treatment of older people (aged 65 years and older) with …

NCCN guidelines® insights: older adult oncology, version 1.2021: featured updates to the NCCN guidelines

E Dotan, LC Walter, IS Browner, K Clifton… - Journal of the National …, 2021 - jnccn.org
The NCCN Guidelines for Older Adult Oncology address specific issues related to the
management of cancer in older adults, including screening and comprehensive geriatric …

Polypharmacy, potentially inappropriate medications, and drug-drug interactions in vulnerable older adults with advanced cancer initiating cancer treatment

E Ramsdale, M Mohamed, V Yu, E Otto, K Juba… - The …, 2022 - academic.oup.com
Purpose Polypharmacy is prevalent in older adults starting cancer treatment and associated
with potentially inappropriate medications (PIM), potential drug-drug interactions (DDI), and …

Polypharmacy and potentially inappropriate medication use in geriatric oncology

M Sharma, KP Loh, G Nightingale, SG Mohile… - Journal of geriatric …, 2016 - Elsevier
Polypharmacy is a highly prevalent problem in older persons, and is challenging to assess
and improve due to variations in definitions of the problem and the heterogeneous methods …

Polypharmacy in elderly patients with cancer: clinical implications and management

J Lees, A Chan - The lancet oncology, 2011 - thelancet.com
More and more elderly people with cancer are treated in oncology clinics worldwide every
year, many of whom have comorbid disorders treated with one or more drugs. Moreover …

Cancer cachexia: impact, mechanisms and emerging treatments

VC Vaughan, P Martin, PA Lewandowski - Journal of cachexia, sarcopenia …, 2013 - Springer
Many forms of cancer present with a complex metabolic profile characterised by loss of lean
body mass known as cancer cachexia. The physical impact of cachexia contributes to …

Patient characteristics associated with polypharmacy and inappropriate prescribing of medications among older adults with cancer

GK Prithviraj, S Koroukian, S Margevicius… - Journal of geriatric …, 2012 - Elsevier
OBJECTIVES: To identify patient characteristics associated with polypharmacy and
inappropriate medication (PIM) use among older patients with newly diagnosed cancer …

Senior adult oncology, version 2.2014

A Hurria, T Wildes, SL Blair, IS Browner… - Journal of the National …, 2014 - jnccn.org
Cancer is the leading cause of death in older adults aged 60 to 79 years. The biology of
certain cancers and responsiveness to therapy changes with the patient's age. Advanced …

[HTML][HTML] Effects of a geriatric assessment intervention on patient-reported symptomatic toxicity in older adults with advanced cancer

E Culakova, SG Mohile, L Peppone… - Journal of Clinical …, 2023 - ncbi.nlm.nih.gov
PURPOSE Providing a geriatric assessment (GA) summary with management
recommendations to oncologists reduces clinician-rated toxicity in older patients with …