Human schistosomiasis

DG Colley, AL Bustinduy, WE Secor, CH King - The Lancet, 2014 - thelancet.com
Human schistosomiasis—or bilharzia—is a parasitic disease caused by trematode flukes of
the genus Schistosoma. By conservative estimates, at least 230 million people worldwide …

Praziquantel for schistosomiasis: single-drug metabolism revisited, mode of action, and resistance

N Vale, MJ Gouveia, G Rinaldi… - Antimicrobial agents …, 2017 - Am Soc Microbiol
Schistosomiasis, a major neglected tropical disease, affects more than 250 million people
worldwide. Treatment of schistosomiasis has relied on the anthelmintic drug praziquantel …

[HTML][HTML] Schistosomiasis with a focus on Africa

OP Aula, DP McManus, MK Jones… - Tropical Medicine and …, 2021 - mdpi.com
Schistosomiasis is a common neglected tropical disease of impoverished people and
livestock in many developing countries in tropical Africa, the Middle East, Asia, and Latin …

[HTML][HTML] Two decades of recent advances of Ugi reactions: synthetic and pharmaceutical applications

MA Fouad, H Abdel-Hamid, MS Ayoup - RSC advances, 2020 - pubs.rsc.org
Multicomponent reactions (MCRs) are powerful synthetic tools in which more than two
starting materials couple with each other to form multi-functionalized compounds in a one …

[HTML][HTML] Impact of human schistosomiasis in sub-Saharan Africa

AF Adenowo, BE Oyinloye, BI Ogunyinka… - Brazilian Journal of …, 2015 - SciELO Brasil
abstract Schistosomiasis, a neglected tropical disease of poverty ranks second among the
most widespread parasitic disease in various nations in sub-Saharan Africa. Neglected …

[HTML][HTML] The roles of water, sanitation and hygiene in reducing schistosomiasis: a review

JET Grimes, D Croll, WE Harrison, J Utzinger… - Parasites & vectors, 2015 - Springer
Schistosomiasis is a disease caused by infection with blood flukes of the genus
Schistosoma. Transmission of, and exposure to, the parasite result from faecal or urinary …

Diagnosis and management of schistosomiasis

DJ Gray, AG Ross, YS Li, DP McManus - Bmj, 2011 - bmj.com
Schistosomiasis, or bilharzia, is a common intravascular infection caused by parasitic
Schistosoma trematode worms. 1 2 A systematic review and meta-analysis published in …

Susceptibility or resistance of praziquantel in human schistosomiasis: a review

W Wang, L Wang, YS Liang - Parasitology research, 2012 - Springer
Since praziquantel was developed in 1970s, it has replaced other antischistosomal drugs to
become the only drug of choice for treatment of human schistosomiases, due to high …

[HTML][HTML] FLOTAC: new multivalent techniques for qualitative and quantitative copromicroscopic diagnosis of parasites in animals and humans

G Cringoli, L Rinaldi, MP Maurelli, J Utzinger - Nature protocols, 2010 - nature.com
Accurate diagnosis of parasitic infections is of pivotal importance for both individual patient
management and population-based studies, such as drug efficacy trials and surveillance of …

[HTML][HTML] HDAC8: a multifaceted target for therapeutic interventions

A Chakrabarti, I Oehme, O Witt, G Oliveira… - Trends in …, 2015 - cell.com
Histone deacetylase 8 (HDAC8) is a class I histone deacetylase implicated as a therapeutic
target in various diseases, including cancer, X-linked intellectual disability, and parasitic …