Development of polymeric nanoparticles for blood–brain barrier transfer—strategies and challenges
Neurological disorders such as Alzheimer's disease, stroke, and brain cancers are difficult to
treat with current drugs as their delivery efficacy to the brain is severely hampered by the …
treat with current drugs as their delivery efficacy to the brain is severely hampered by the …
Glycopolymer-functionalized MOF-808 nanoparticles as a cancer-targeted dual drug delivery system for carboplatin and floxuridine
F Demir Duman, A Monaco, R Foulkes… - ACS Applied Nano …, 2022 - ACS Publications
Codelivery of chemotherapeutics via nanomaterials has attracted much attention over the
last decades due to improved drug delivery to tumor tissues, decreased systemic effects …
last decades due to improved drug delivery to tumor tissues, decreased systemic effects …
Poly-ε-caprolactone (PCL), a promising polymer for pharmaceutical and biomedical applications: Focus on nanomedicine in cancer
SM Espinoza, HI Patil, ESM Martinez… - … Journal of Polymeric …, 2019 - Taylor & Francis
Abstract Poly-ε-caprolactone (PCL) has been the subject of extensive research in the past
few years. It is widely explored in drug delivery, where the development of nanomedicines …
few years. It is widely explored in drug delivery, where the development of nanomedicines …
Evolving therapeutic strategies to exploit chromosome instability in cancer
LL Thompson, LMP Jeusset, CC Lepage, KJ McManus - Cancers, 2017 - mdpi.com
Cancer is a devastating disease that claims over 8 million lives each year. Understanding
the molecular etiology of the disease is critical to identify and develop new therapeutic …
the molecular etiology of the disease is critical to identify and develop new therapeutic …
Drug-delivery nanoparticles for bone-tissue and dental applications
T Higino, R França - Biomedical Physics & Engineering Express, 2022 - iopscience.iop.org
The use of nanoparticles as biomaterials with applications in the biomedical field is growing
every day. These nanomaterials can be used as contrast imaging agents, combination …
every day. These nanomaterials can be used as contrast imaging agents, combination …
Polymeric nanoparticles as carrier for targeted and controlled delivery of anticancer agents
V Taghipour-Sabzevar, T Sharifi… - Therapeutic …, 2019 - Taylor & Francis
In recent decades, many novel methods by using nanoparticles (NPs) have been
investigated for diagnosis, drug delivery and treatment of cancer. Accordingly, the potential …
investigated for diagnosis, drug delivery and treatment of cancer. Accordingly, the potential …
In-vitro investigation of the anticancer efficacy of carboplatin-loaded chitosan nanocomposites against breast and liver cancer cell lines
One of the critical issues in the cancer tussle is the innovation of drug delivery platforms for
the extremely selective, controlled, and sustained release of anti-cancer drugs. We herein …
the extremely selective, controlled, and sustained release of anti-cancer drugs. We herein …
Characterization and carboplatin loaded chitosan nanoparticles for the chemotherapy against breast cancer in vitro studies
MA Khan, M Zafaryab, SH Mehdi, J Quadri… - International journal of …, 2017 - Elsevier
Aim of the studies to synthesized chitosan nanoparticles by an ionic interaction procedure.
The nanoparticles were characterized by physicochemical methods like, DLS, TEM, Surface …
The nanoparticles were characterized by physicochemical methods like, DLS, TEM, Surface …
Branched Poly(ε-caprolactone)-Based Copolyesters of Different Architectures and Their Use in the Preparation of Anticancer Drug-Loaded Nanoparticles
E Christodoulou, M Notopoulou, E Nakiou… - International Journal of …, 2022 - mdpi.com
Limitations associated with the use of linear biodegradable polyesters in the preparation of
anticancer nano-based drug delivery systems (nanoDDS) have turned scientific attention to …
anticancer nano-based drug delivery systems (nanoDDS) have turned scientific attention to …
Improved antitumor activity and reduced toxicity of doxorubicin encapsulated in poly (ε-caprolactone) nanoparticles in lung and breast cancer treatment: An in vitro and …
Abstract Poly (ε-caprolactone)(PCL) nanoparticles (NPs) offer many possibilities for drug
transport because of their good physicochemical properties and biocompatibility …
transport because of their good physicochemical properties and biocompatibility …