The MYC oncogene is a global regulator of the immune response

SC Casey, V Baylot, DW Felsher - Blood, The Journal of the …, 2018 - ashpublications.org
The MYC proto-oncogene is a gene product that coordinates the transcriptional regulation of
a multitude of genes that are essential to cellular programs required for normal as well as …

Immunosuppressive B cells expressing PD-1/PD-L1 in solid tumors: a mini review

X Sun, T Zhang, M Li, L Yin, J Xue - QJM: An International …, 2022 - academic.oup.com
Expression of programmed cell death-1 (PD-1/CD279) on T cells and the ligand of PD-1,
programmed death ligand-1 (PD-L1)(CD274/B7-H1) on tumor cells or other immune cells …

B-cell receptor–mediated NFATc1 activation induces IL-10/STAT3/PD-L1 signaling in diffuse large B-cell lymphoma

L Li, J Zhang, J Chen, ZY Xu-Monette… - Blood, The Journal …, 2018 - ashpublications.org
Abstract Knowledge of programmed death ligand 1 (PD-L1) expression and its regulation in
B-cell lymphoma cells is limited. Investigating mechanisms that control PD-L1 expression in …

[HTML][HTML] Modulating PD-L1 expression in multiple myeloma: an alternative strategy to target the PD-1/PD-L1 pathway

R Tremblay-LeMay, N Rastgoo, H Chang - Journal of hematology & …, 2018 - Springer
Even with recent advances in therapy regimen, multiple myeloma patients commonly
develop drug resistance and relapse. The relevance of targeting the PD-1/PD-L1 axis has …

Autologous dendritic cell-cytokine induced killer cell immunotherapy combined with S-1 plus cisplatin in patients with advanced gastric cancer: a prospective study

G Qiao, X Wang, L Zhou, X Zhou, Y Song, S Wang… - Clinical Cancer …, 2019 - AACR
Purpose: We have assessed the combination of DC–CIK with S-1 plus cisplatin
chemotherapy in advanced gastric cancer (AGC) and the role of mutational analysis of …

Combination of attenuated Salmonella carrying PD‐1 siRNA with nifuroxazide for colon cancer therapy

T Zhao, Y Feng, M Guo, C Zhang, Q Wu… - Journal of Cellular …, 2020 - Wiley Online Library
Colon cancer is a member of malignant tumors in the digestive system. Traditional treatment
strategies are ineffective and improving the treatment of colon cancer is an urgent need …

The roles of programmed cell death ligand-1/programmed cell death-1 (PD-L1/PD-1) in HPV-induced cervical cancer and potential for their use in blockade therapy

L Zhang, Y Zhao, Q Tu, X Xue, X Zhu… - Current Medicinal …, 2021 - ingentaconnect.com
Background: Cervical cancer induced by infection with human papillomavirus (HPV)
remains a leading cause of mortality for women worldwide although preventive vaccines …

STAT3 as a potential immunotherapy biomarker in oncogene-addicted non-small cell lung cancer

I Attili, N Karachaliou, L Bonanno… - Therapeutic …, 2018 - journals.sagepub.com
Immune checkpoint blockade has modified the treatment landscape for many types of
tumors, including lung cancer. Still our knowledge on the biology of the interaction between …

[HTML][HTML] miR-101, miR-548b, miR-554, and miR-1202 are reliable prognosis predictors of the miRNAs associated with cancer immunity in primary central nervous …

Y Takashima, A Kawaguchi, Y Iwadate, H Hondoh… - PLoS …, 2020 - journals.plos.org
MicroRNAs (miRNAs) inhibit protein function by silencing the translation of target mRNAs.
However, in primary central nervous system lymphoma (PCNSL), the expression and …

[HTML][HTML] Regorafenib induces damage-associated molecular patterns, cancer cell death and immune modulatory effects in a murine triple negative breast cancer …

LM Tseng, KY Lau, JL Chen, PY Chu, TT Huang… - Experimental Cell …, 2023 - Elsevier
Damage associated molecular patterns (DAMPs), including calreticulin (CRT) exposure,
high-mobility group box 1 protein (HMGB1) elevation, and ATP release, characterize …