Alzheimer's disease (AD), the most common neurodegenerative disorder associated with
dementia, not only severely decreases the quality of life for its victims, but also brings a …

Alzheimer's disease (AD) is a complex neurodegenerative disorder that affects multiple
brain regions and is difficult to treat. In this study we used 22 AD large-scale gene …

Low birth rates and increasing life expectancy experienced by developed societies have
placed an unprecedented pressure on governments and the health system to deal …

N‐Methyl‐D‐aspartate receptors (NMDARs) have two opposing roles in the brain. On the
one hand, NMDARs control critical events in the formation and development of synaptic …

Berberine, an important protoberberine isoquinoline alkaloid, has several pharmacological
activities, including antimicrobial, glucose-and cholesterol-lowering, antitumoral, and …

Alzheimer's disease (AD) is a common neurodegenerative disease that often occurs in the
elderly population. At present, most drugs for AD on the market are single-target drugs …

Natural products, being richly endowed with curative powers, have become spotlight for
biomedical and pharmaceutical research to develop novel therapeutics during recent years …

Mitochondria are physically and biochemically in contact with other organelles including the
endoplasmic reticulum (ER). Such contacts are formed between mitochondria‐associated …

A growing body of evidence currently proposes that deep learning approaches can serve as
an essential cornerstone for the diagnosis and prediction of Alzheimer's disease (AD). In …

Microglia are the innate immune cells of the brain, which maintain homeostasis by
constantly scanning and surveying the environment with their highly ramified processes. In …