Deep learning with neuroimaging and genomics in Alzheimer's disease
A growing body of evidence currently proposes that deep learning approaches can serve as
an essential cornerstone for the diagnosis and prediction of Alzheimer's disease (AD). In …
an essential cornerstone for the diagnosis and prediction of Alzheimer's disease (AD). In …
Long noncoding RNAs and Alzheimer's disease
Q Luo, Y Chen - Clinical interventions in aging, 2016 - Taylor & Francis
Long noncoding RNAs (lncRNAs) are typically defined as transcripts longer than 200
nucleotides. lncRNAs can regulate gene expression at epigenetic, transcriptional, and …
nucleotides. lncRNAs can regulate gene expression at epigenetic, transcriptional, and …
A review on mitochondrial restorative mechanism of antioxidants in Alzheimer's disease and other neurological conditions
A Kumar, A Singh - Frontiers in pharmacology, 2015 - frontiersin.org
Neurodegenerative diseases are intricate in nature because of the involvement of the
multiple pathophysiological events including mitochondrial dysfunction, neuroinflammation …
multiple pathophysiological events including mitochondrial dysfunction, neuroinflammation …
Comprehensive insight into the molecular interaction of rutin with human transferrin: Implication of natural compounds in neurodegenerative diseases
Neurodegeneration, a process of irreversible neuronal damage, is characterized by a
damaged neuronal structure and function. The interplay between various proteins maintains …
damaged neuronal structure and function. The interplay between various proteins maintains …
Periodontal disease, tooth loss and dementia: Is there a link? A systematic review
PP Tonsekar, SS Jiang, G Yue - Gerodontology, 2017 - Wiley Online Library
Background It has been suggested that dementia is caused by neuronal damage due to
chronic inflammation from peripheral sources such as the oral cavity in periodontal disease …
chronic inflammation from peripheral sources such as the oral cavity in periodontal disease …
Autophagy and mitophagy biomarkers are reduced in sera of patients with Alzheimer's disease and mild cognitive impairment
Dementia is a neurocognitive disorder characterized by a progressive memory loss and
impairment in cognitive and functional abilities. Autophagy and mitophagy are two important …
impairment in cognitive and functional abilities. Autophagy and mitophagy are two important …
Dietary pattern, gut microbiota, and Alzheimer's disease
Alzheimer's disease is the most common neurodegenerative disease. Until now, there has
been no specific medicine that can cure Alzheimer's disease or effectively reverse the …
been no specific medicine that can cure Alzheimer's disease or effectively reverse the …
The potential role of cytokines and growth factors in the pathogenesis of Alzheimer's disease
G Ogunmokun, S Dewanjee, P Chakraborty… - Cells, 2021 - mdpi.com
Alzheimer's disease (AD) is one of the most prominent neurodegenerative diseases, which
impairs cognitive function in afflicted individuals. AD results in gradual decay of neuronal …
impairs cognitive function in afflicted individuals. AD results in gradual decay of neuronal …
Pyrazoline containing compounds as therapeutic targets for neurodegenerative disorders
Pyrazolines are a significant class of heterocyclic compounds with essential biological
activities. They are quite stable, which has inspired medicinal chemists to experiment with …
activities. They are quite stable, which has inspired medicinal chemists to experiment with …
The effects of domestication on secondary metabolite composition in legumes
YS Ku, CA Contador, MS Ng, J Yu, G Chung… - Frontiers in …, 2020 - frontiersin.org
Legumes are rich in secondary metabolites, such as polyphenols, alkaloids, and saponins,
which are important defense compounds to protect the plant against herbivores and …
which are important defense compounds to protect the plant against herbivores and …