Deep learning with neuroimaging and genomics in Alzheimer's disease

E Lin, CH Lin, HY Lane - International journal of molecular sciences, 2021 - mdpi.com
A growing body of evidence currently proposes that deep learning approaches can serve as
an essential cornerstone for the diagnosis and prediction of Alzheimer's disease (AD). In …

Long noncoding RNAs and Alzheimer's disease

Q Luo, Y Chen - Clinical interventions in aging, 2016 - Taylor & Francis
Long noncoding RNAs (lncRNAs) are typically defined as transcripts longer than 200
nucleotides. lncRNAs can regulate gene expression at epigenetic, transcriptional, and …

A review on mitochondrial restorative mechanism of antioxidants in Alzheimer's disease and other neurological conditions

A Kumar, A Singh - Frontiers in pharmacology, 2015 - frontiersin.org
Neurodegenerative diseases are intricate in nature because of the involvement of the
multiple pathophysiological events including mitochondrial dysfunction, neuroinflammation …

Comprehensive insight into the molecular interaction of rutin with human transferrin: Implication of natural compounds in neurodegenerative diseases

A Shamsi, M Furkan, RH Khan, MS Khan… - International journal of …, 2023 - Elsevier
Neurodegeneration, a process of irreversible neuronal damage, is characterized by a
damaged neuronal structure and function. The interplay between various proteins maintains …

Periodontal disease, tooth loss and dementia: Is there a link? A systematic review

PP Tonsekar, SS Jiang, G Yue - Gerodontology, 2017 - Wiley Online Library
Background It has been suggested that dementia is caused by neuronal damage due to
chronic inflammation from peripheral sources such as the oral cavity in periodontal disease …

Autophagy and mitophagy biomarkers are reduced in sera of patients with Alzheimer's disease and mild cognitive impairment

M Castellazzi, S Patergnani, M Donadio, C Giorgi… - Scientific reports, 2019 - nature.com
Dementia is a neurocognitive disorder characterized by a progressive memory loss and
impairment in cognitive and functional abilities. Autophagy and mitophagy are two important …

Dietary pattern, gut microbiota, and Alzheimer's disease

M Zhang, D Zhao, G Zhou, C Li - Journal of agricultural and food …, 2020 - ACS Publications
Alzheimer's disease is the most common neurodegenerative disease. Until now, there has
been no specific medicine that can cure Alzheimer's disease or effectively reverse the …

The potential role of cytokines and growth factors in the pathogenesis of Alzheimer's disease

G Ogunmokun, S Dewanjee, P Chakraborty… - Cells, 2021 - mdpi.com
Alzheimer's disease (AD) is one of the most prominent neurodegenerative diseases, which
impairs cognitive function in afflicted individuals. AD results in gradual decay of neuronal …

Pyrazoline containing compounds as therapeutic targets for neurodegenerative disorders

MJ Ahsan, A Ali, A Ali, A Thiriveedhi, MA Bakht… - ACS …, 2022 - ACS Publications
Pyrazolines are a significant class of heterocyclic compounds with essential biological
activities. They are quite stable, which has inspired medicinal chemists to experiment with …

The effects of domestication on secondary metabolite composition in legumes

YS Ku, CA Contador, MS Ng, J Yu, G Chung… - Frontiers in …, 2020 - frontiersin.org
Legumes are rich in secondary metabolites, such as polyphenols, alkaloids, and saponins,
which are important defense compounds to protect the plant against herbivores and …