Enalapril: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension and congestive heart failure

PA Todd, RC Heel - Drugs, 1986 - Springer
Synopsis: Enalapril maleate 1 is an orally active angiotensin-converting enzyme inhibitor. It
lowers peripheral vascular resistance without causing an increase in heart rate. Enalapril 10 …

Angiotensin converting enzyme inhibitors and moderate hypertension

D McAreavey, JIS Robertson - Drugs, 1990 - Springer
Recently there has been extensive development of orally active angiotensin converting
enzyme (ACE) inhibitors in addition to those already marketed, for example, captopril …

Cellular mechanisms of metabolic syndrome-related atrial decompensation in a rat model of HFpEF

F Hohendanner, D Bode, U Primessnig, T Guthof… - Journal of molecular and …, 2018 - Elsevier
Heart failure (HF) with preserved ejection fraction (HFpEF) is present in about 50% of HF
patients. Atrial remodeling is common in HFpEF and associated with increased mortality. We …

Effect of enalapril in subjects with hypertension associated with moderate to severe renal dysfunction

GP Reams, JH Bauer - Archives of internal medicine, 1986 - jamanetwork.com
• The purpose of this study was to define the effect of the angiotensin-converting enzyme
inhibitor, enalapril maleate, on blood pressure, renal function, protein excretion, and …

Comparison of effects of enalapril plus hydrochlorothiazide versus standard triple therapy on renal function in renovascular hypertension

SS Franklin, RD Smith - The American journal of medicine, 1985 - Elsevier
Renal function and antihypertensive drug efficacy were determined in a prospective, double-
blind, multicenter study comparing enalapril plus hydrochlorothiazide with standard triple …

Effects of antihypertensive treatment in one–clip, two kidney hypertension in rats

JB Michel, JC Dussaule, L Choudat, C Auzan… - Kidney international, 1986 - Elsevier
Effects of antihypertensive treatment in one–clip, two kidney hypertension in rats. In order to
investigate the consequences of antihypertensive therapy on hormonal and renal …

Evaluation and management of bilateral renal artery stenosis in children: a case series and review

D Ellis, R Shapiro, VP Scantlebury, R Simmons… - Pediatric …, 1995 - Springer
This report describes the clinical course, diagnostic evaluation and management of six
children with bilateral renal artery stenosis (RAS) and concurrent narrowing of the …

Enalapril: a new angiotensin converting enzyme inhibitor

JD Cleary, JW Taylor - Drug intelligence & clinical pharmacy, 1986 - journals.sagepub.com
Enalapril maleate is a new angiotensin converting enzyme inhibitor marketed in the US by
Merck Sharp and Dohme. It has been demonstrated to actively interfere with the renin …

The renin-angiotensin system in the twenty-first century

M Gary Nicholls, JIS Robertson, T Inagami - Blood pressure, 2001 - Taylor & Francis
Renin was discovered more than a century ago as a pressor principle in renal extracts.
Subsequent research has revealed the renin-angiotensin system to be fascinatingly …

Pharmacology of angiotensin converting enzyme inhibitors: A review

EB Nelson, JL Pool, AA Taylor - The American journal of medicine, 1986 - Elsevier
Two angiotensin converting enzyme inhibitors are currently available for clinical use.
Captopril, a sulfhydryl-containing compound, is a direct acting enzyme inhibitor. Enalapril is …