Recent synthetic strategies for the construction of functionalized carbazoles and their heterocyclic motifs enabled by Lewis acids

MP Kumar, G Mahantesh, P Amaladass… - RSC …, 2023 - pubs.rsc.org
This article demonstrates recent innovative cascade annulation methods for preparing
functionalized carbazoles and their related polyaromatic heterocyclic compounds enabled …

Synthesis, antibacterial and antioxidant activities of Thiazole-based Schiff base derivatives: a combined experimental and computational study

F Lemilemu, M Bitew, TB Demissie, R Eswaramoorthy… - BMC chemistry, 2021 - Springer
Abstract Background Thiazole-based Schiff base compounds display significant
pharmacological potential with an ability to modulate the activity of many enzymes involved …

Synthesis, characterization, and biological activities of novel vanadium (IV) and cobalt (II) complexes

T Damena, D Zeleke, T Desalegn, TB Demissie… - ACS …, 2022 - ACS Publications
Herein, we report novel Co (II) and V (IV) complexes synthesized from an (E)-2-(((2-((2-
hydroxyethyl) amino) quinolin-3-yl) methylene) amino) ethan-1-ol ligand (L), cobalt (II) …

Pro-inflammatory cytokine molecules from Boswellia serrate suppresses lipopolysaccharides induced inflammation demonstrated in an in-vivo zebrafish larval model

NSS Siddhu, A Guru, RC Satish Kumar… - Molecular Biology …, 2022 - Springer
Background Boswellia serrate is an ancient and highly valued ayurvedic herb. Its extracts
have been used in medicine for centuries to treat a wide variety of chronic inflammatory …

Antimicrobial activity, in silico molecular docking, ADMET and DFT analysis of secondary metabolites from roots of three Ethiopian medicinal plants

M Anza, M Endale, L Cardona, D Cortes… - … and Applications in …, 2021 - Taylor & Francis
Background Uvaria scheffleri (Annonaceae), Clematis burgensis (Ranunculaceae), and
Euphorbia schimperiana (Euphorbiaceae) are medicinal plants traditionally used to treat …

Screening of Anti-Lipase Components of Artemisia argyi Leaves Based on Spectrum-Effect Relationships and HPLC-MS/MS

Y Chang, D Zhang, G Yang, Y Zheng… - Frontiers in …, 2021 - frontiersin.org
Pancreatic lipase is a key lipase for triacylglyceride digestion and absorption, which is
recognized as a promising target for treatment of metabolic disorders. Natural …

GC-MS Profiling, Vibriocidal, Antioxidant, Antibiofilm, and Anti-Quorum Sensing Properties of Carum carvi L. Essential Oil: In Vitro and In Silico Approaches

S Ghannay, K Aouadi, A Kadri, M Snoussi - Plants, 2022 - mdpi.com
The main objectives of the present study were to investigate anti-Vibrio spp., antibiofilms,
and anti-quorum-sensing (anti-QS) properties of caraway essential oil in relation to their …

Potential energy surface, effect of solvents in molecular level, experimental spectra (FTIR, Raman, UV–visible & NMR), electronic, and dynamics simulation of …

N Mani, D Nicksonsebastin, M Prasath… - Journal of Molecular …, 2023 - Elsevier
The spectroscopic characteristics, molecular structure, and biological characteristics of the
Isobavachalcone (IBC) structure have been studied using computational techniques utilizing …

Effect of different solvents, molecular level vibrational energies, electronic, electrostatic, donar-acceptor and pharmaceutical studies on 3-methoxy phenyl acetonitrile …

S Rekha, S Tamilselvan, V Vetrivelan… - Journal of Molecular …, 2023 - Elsevier
The most economical method for analyzing molecular structure is density functional theory
(DFT), which has several applications in the study of vibrational spectrum biological …

Discovery of phenylcarbamoylazinane-1, 2, 4-triazole amides derivatives as the potential inhibitors of aldo-keto reductases (AKR1B1 & AKRB10): Potential lead …

A Saeed, SA Ejaz, M Sarfraz, N Tamam, F Siddique… - Molecules, 2022 - mdpi.com
Both members of the aldo-keto reductases (AKRs) family, AKR1B1 and AKR1B10, are over-
expressed in various type of cancer, making them potential targets for inflammation …