A review of inflammatory mechanism in airway diseases

P Aghasafari, U George, R Pidaparti - Inflammation Research, 2019 - Springer
Background Inflammation in the lung is the body's natural response to injury. It acts to
remove harmful stimuli such as pathogens, irritants, and damaged cells and initiate the …

The gut-lung axis in cystic fibrosis

CE Price, GA O'Toole - Journal of bacteriology, 2021 - Am Soc Microbiol
Cystic fibrosis (CF) is a heritable, multiorgan disease that impacts all tissues that normally
express cystic fibrosis transmembrane conductance regulator (CFTR) protein. While the …

IL-1β, IL-23, and TGF-β drive plasticity of human ILC2s towards IL-17-producing ILCs in nasal inflammation

K Golebski, XR Ros, M Nagasawa, S van Tol… - Nature …, 2019 - nature.com
Innate lymphoid cells (ILCs) are crucial for the immune surveillance at mucosal sites. ILCs
coordinate early eradication of pathogens and contribute to tissue healing and remodeling …

The role of fibroblast growth factor 23 in inflammation and anemia

B Czaya, C Faul - International journal of molecular sciences, 2019 - mdpi.com
In patients with chronic kidney disease (CKD), adverse outcomes such as systemic
inflammation and anemia are contributing pathologies which increase the risks for …

Sputum biomarkers of inflammation in cystic fibrosis lung disease

SD Sagel, JF Chmiel, MW Konstan - Proceedings of the American …, 2007 - atsjournals.org
Pulmonary biomarkers are being used more frequently to monitor disease activity and
evaluate response to treatment in individuals with cystic fibrosis (CF). This article …

Volatile organic compounds in the exhaled breath of young patients with cystic fibrosis

M Barker, M Hengst, J Schmid, HJ Buers… - European …, 2006 - Eur Respiratory Soc
Inflammatory mediators in the exhaled breath are receiving growing medical interest as
noninvasive disease markers. Volatile organic compounds have been investigated in this …

The role of microRNAs in chronic respiratory disease: recent insights

LR Stolzenburg, A Harris - Biological chemistry, 2018 - degruyter.com
Chronic respiratory diseases encompass a group of diverse conditions affecting the airways,
which all impair lung function over time. They include cystic fibrosis (CF), idiopathic …

Mycobacterium abscessus-Induced Granuloma Formation Is Strictly Dependent on TNF Signaling and Neutrophil Trafficking

A Bernut, M Nguyen-Chi, I Halloum… - PLoS …, 2016 - journals.plos.org
Mycobacterium abscessus is considered the most common respiratory pathogen among the
rapidly growing non-tuberculous mycobacteria. Infections with M. abscessus are …

G-CSF and GM-CSF modify neutrophil functions at concentrations found in cystic fibrosis

S Castellani, S D'Oria, A Diana, AM Polizzi… - Scientific Reports, 2019 - nature.com
The role of colony stimulating factors (CSFs) in cystic fibrosis (CF) circulating neutrophils has
not been thoroughly evaluated, considering that the neutrophil burden of lung inflammation …

What's new in cystic fibrosis? From treating symptoms to correction of the basic defect

M Proesmans, F Vermeulen, K De Boeck - European journal of pediatrics, 2008 - Springer
Chronic relentless lung infection and pancreatic insufficiency are the cardinal features of
cystic fibrosis (CF), a life-shortening autosomal recessive disease. Mutations in the'cystic …