[HTML][HTML] Mitochondrial redox signaling and oxidative stress in kidney diseases
Mitochondria are essential organelles in physiology and kidney diseases, because they
produce cellular energy required to perform their function. During mitochondrial metabolism …
produce cellular energy required to perform their function. During mitochondrial metabolism …
[HTML][HTML] The interplay between immune and metabolic pathways in kidney disease
Kidney disease is a significant health problem worldwide, affecting an estimated 10% of the
global population. Kidney disease encompasses a diverse group of disorders that vary in …
global population. Kidney disease encompasses a diverse group of disorders that vary in …
[HTML][HTML] PGC-1α inhibits the NLRP3 inflammasome via preserving mitochondrial viability to protect kidney fibrosis
The NLRP3 inflammasome is activated by mitochondrial damage and contributes to kidney
fibrosis. However, it is unknown whether PGC-1α, a key mitochondrial biogenesis regulator …
fibrosis. However, it is unknown whether PGC-1α, a key mitochondrial biogenesis regulator …
[HTML][HTML] Oxidative stress and mitochondrial dysfunction in chronic kidney disease
HJ Ho, H Shirakawa - Cells, 2022 - mdpi.com
The kidney contains many mitochondria that generate ATP to provide energy for cellular
processes. Oxidative stress injury can be caused by impaired mitochondria with excessive …
processes. Oxidative stress injury can be caused by impaired mitochondria with excessive …
[HTML][HTML] Melatonin as a therapeutic agent for alleviating endothelial dysfunction in cardiovascular diseases: Emphasis on oxidative stress
X Zhang, Y Zheng, Z Wang, J Gan, B Yu, B Lu… - Biomedicine & …, 2023 - Elsevier
The vascular endothelium is vital in maintaining cardiovascular health by regulating
vascular permeability and tone, preventing thrombosis, and controlling vascular …
vascular permeability and tone, preventing thrombosis, and controlling vascular …
Interactions between mitochondrial dysfunction and other hallmarks of aging: Paving a path toward interventions that promote healthy old age
Current research on human aging has largely been guided by the milestone paper
“hallmarks of aging,” which were first proposed in the seminal 2013 paper by Lopez‐Otin et …
“hallmarks of aging,” which were first proposed in the seminal 2013 paper by Lopez‐Otin et …
Mitochondrial dysfunction and oxidative stress: Role in chronic kidney disease
A Srivastava, B Tomar, D Sharma, SK Rath - Life Sciences, 2023 - Elsevier
Chronic kidney disease (CKD) is associated with a variety of distinct disease processes that
permanently change the function and structure of the kidney across months or years. CKD is …
permanently change the function and structure of the kidney across months or years. CKD is …
Limiting mitochondrial plasticity by targeting DRP1 induces metabolic reprogramming and reduces breast cancer brain metastases
Disseminated tumor cells with metabolic flexibility to utilize available nutrients in distal
organs persist, but the precise mechanisms that facilitate metabolic adaptations remain …
organs persist, but the precise mechanisms that facilitate metabolic adaptations remain …
[HTML][HTML] Renal-protective roles of lipoic acid in kidney disease
SF Kamt, J Liu, LJ Yan - Nutrients, 2023 - mdpi.com
The kidney is a crucial organ that eliminates metabolic waste and reabsorbs nutritious
elements. It also participates in the regulation of blood pressure, maintenance of electrolyte …
elements. It also participates in the regulation of blood pressure, maintenance of electrolyte …
Reactive X (where X= O, N, S, C, Cl, Br, and I) species nanomedicine
Reactive oxygen, nitrogen, sulfur, carbonyl, chlorine, bromine, and iodine species (RXS,
where X= O, N, S, C, Cl, Br, and I) have important roles in various normal physiological …
where X= O, N, S, C, Cl, Br, and I) have important roles in various normal physiological …