Plasmacytoid dendritic cells (pDCs) are a unique subset of cells with different functional
characteristics compared to classical dendritic cells. The pDCs are critical for the production …

Background Immune markers in the peripheral blood of melanoma patients provide useful
information for clinical management although there is poor consensus on circulating cells …

This study aims at screening out the key necroptosis-related genes in colorectal cancer and
elucidating the role of necroptosis-related genes in the immune activity and prognosis of …

The defense mechanism of the immune system is based on the interaction of many kinds of
leukocytes. Among them, dendritic cells (DCs) control most immune responses. In our …

In the last 20 years, dendritic cells (DCs) have been largely used as a platform for
therapeutic vaccination in cancer patients. However, despite its proven safety and ability to …

Microsatellite instability (MSI) is characterized by a highly immunogenic tumor phenotype
and abundant lymphocytic infiltrates. The aim of this study was to investigate the association …

Multiple pathogenic mechanisms contribute to the development of colorectal cancer. This
tumor is characterized by high chemoresistance and low immunogenicity due to the effective …

Monoclonal antibodies recognizing programmed death‑ligand 1 (PD‑L1) have been used for
the clinical treatment of diverse tumor types as a form of immune checkpoint inhibitor, with a …

Целью исследования явилось изучение особенностей взаимосвязи между фенотипом
и активностью «респираторного взрыва» нейтрофильных гранулоцитов у больных …

Purpose CXCR5-positive (CXCR5+) tumor cell infiltration has different prognostic values in
different types of cancer. The objective was to evaluate the effect of CXCR5+ cell infiltration …