Pathogenesis of allergic diseases and implications for therapeutic interventions

J Wang, Y Zhou, H Zhang, L Hu, J Liu, L Wang… - Signal transduction and …, 2023 - nature.com
Allergic diseases such as allergic rhinitis (AR), allergic asthma (AAS), atopic dermatitis (AD),
food allergy (FA), and eczema are systemic diseases caused by an impaired immune …

Atopic dermatitis endotypes and implications for targeted therapeutics

T Czarnowicki, H He, JG Krueger… - Journal of Allergy and …, 2019 - Elsevier
Recent research advancements indicate that atopic dermatitis (AD) is a complex disease
characterized by different subtypes/phenotypes based on age, disease chronicity, ethnicity …

The how and why of lncRNA function: an innate immune perspective

EK Robinson, S Covarrubias, S Carpenter - Biochimica et Biophysica Acta …, 2020 - Elsevier
Next-generation sequencing has provided a more complete picture of the composition of the
human transcriptome indicating that much of the “blueprint” is a vastness of poorly …

Perinatal and early-life nutrition, epigenetics, and allergy

N Acevedo, B Alashkar Alhamwe, L Caraballo, M Ding… - Nutrients, 2021 - mdpi.com
Epidemiological studies have shown a dramatic increase in the incidence and the
prevalence of allergic diseases over the last several decades. Environmental triggers …

Modulating epigenetic modifications for cancer therapy

LJ Castro-Muñoz, EV Ulloa, C Sahlgren… - Oncology …, 2023 - spandidos-publications.com
Cancer is a global public health concern. Alterations in epigenetic processes are among the
earliest genomic aberrations occurring during cancer development and are closely related …

Metabolism and epigenetics at the heart of T cell function

L Soriano-Baguet, D Brenner - Trends in immunology, 2023 - cell.com
T cell subsets adapt and rewire their metabolism according to their functions and
surrounding microenvironment. Whereas naive T cells rely on mitochondrial metabolic …

The complex role of MEG3: An emerging long non-coding RNA in breast cancer

MS Hussain, AA Majami, H Ali, G Kumar… - … -Research and Practice, 2023 - Elsevier
MEG3, a significant long non-coding RNA (lncRNA), substantially functions in diverse
biological processes, particularly breast cancer (BC) development. Within the imprinting …

Role of personalized nutrition in chronic-degenerative diseases

L Di Renzo, P Gualtieri, L Romano, G Marrone, A Noce… - Nutrients, 2019 - mdpi.com
Human nutrition is a branch of medicine based on foods biochemical interactions with the
human body. The phenotypic transition from health to disease status can be attributed to …

Decoding the genetic and epigenetic basis of asthma

BS Stikker, RW Hendriks, R Stadhouders - Allergy, 2023 - Wiley Online Library
Asthma is a complex and heterogeneous chronic inflammatory disease of the airways.
Alongside environmental factors, asthma susceptibility is strongly influenced by genetics …

The impact of milk and its components on epigenetic programming of immune function in early life and beyond: implications for allergy and asthma

BCAM Esch, M Porbahaie, S Abbring… - Frontiers in …, 2020 - frontiersin.org
Specific and adequate nutrition during pregnancy and early life is an important factor in
avoiding non-communicable diseases such as obesity, type 2 diabetes, cardiovascular …