Connexins are chordate gap junction channel proteins that, by enabling direct
communication between the cytosols of adjacent cells, create a unique cell signalling …

Summry—Gap junctions are widely expressed in the various cell types of the central
nervous system. These specialized membrane intercellular junctions provide the …

Heterocellular electrotonic coupling between cardiac myocytes and non-excitable
connective tissue cells has been a long-established and well-researched fact in vitro …

Exposure of cells to any form of ionizing radiation (IR) is expected to induce a variety of DNA
lesions, including double strand breaks (DSBs), single strand breaks (SSBs) and oxidized …

Compiling significant advances from more than a decade of research, this text presents
breakthroughs in the prevention, treatment, and control of cancer-exploring the origin …

Understanding the factors that allow biological systems to reliably self‐assemble consistent,
highly complex, four dimensional patterns on many scales is crucial for the biomedicine of …

Under normal homeostasis, melanocyte growth and behaviour is tightly controlled by the
surrounding keratinocytes. Keratinocytes regulate melanocyte behaviour through a complex …

The principle of using suicide genes for gene directed enzyme prodrug therapy (GDEPT) of
cancer has gained increasing significance during the 20 years since its inception. The astute …

The gap junction gene connexin 43 (Cx43) showed tumor-suppressing effects on various
tumor cell lines. We have previously demonstrated that Cx43 inhibited expression of S …

The expression of the gap-junction proteins connexin (CX) 43 and 32 was evaluated in
surgical specimens of brain tumors and perilesional cortex from patients with chronic …