For all microorganisms, acquisition of metal ions is essential for survival in the environment
or in their infected host. Metal ions are required in many biological processes as …

A revolution occurred during the last decade in the comprehension of the physiology as well
as in the physiopathology of iron metabolism. The purpose of this review is to summarize the …

Iron is an indispensable metabolic cofactor in both pro-and eukaryotes, which engenders a
natural competition for the metal between bacterial pathogens and their human or animal …

Siderophores are low molecular weight, high affinity iron chelating molecules that are
essential virulence factors in many Gram-negative bacterial pathogens. Whereas the …

Bacterial pathogens must overcome host sequestration of zinc (Zn 2+), an essential
micronutrient, during the infectious disease process. While the mechanisms to acquire …

Aerobactin is a citrate-hydroxamate siderophore that is critical for the virulence of
pathogenic enteric bacteria. However, although the aerobactin-producing iucABCD-iutA …

Bacterial endosymbionts exert a variety of beneficial effects on insect hosts. In pea aphids
(Acyrthosiphon pisum), several inherited endosymbiont species protect their hosts against …

Low molecular weight siderophores are used by many living organisms to scavenge
scarcely available ferric iron. Presence of at least a single siderophore-based iron …

A number of bacterial pathogens require the ZnuABC Zinc (Zn2+) transporter and/or a
second Zn2+ transport system to overcome Zn2+ sequestration by mammalian hosts …

Little is known about Zn homeostasis in Yersinia pestis, the plague bacillus. The Znu ABC
transporter is essential for zinc (Zn) uptake and virulence in a number of bacterial …