European Heart rhythm association (EHRA)/European association of cardiovascular prevention and rehabilitation (EACPR) position paper on how to prevent atrial …
EP Europace, 2017 - academic.oup.com
Atrial fibrillation (AF) is an important and highly prevalent arrhythmia, which is associated
with significantly increased morbidity and mortality, including a four-to five-fold increased …
with significantly increased morbidity and mortality, including a four-to five-fold increased …
New strategies for the treatment of atrial fibrillation
Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia in the clinical practice. It
significantly contributes to the morbidity and mortality of the elderly population. Over the past …
significantly contributes to the morbidity and mortality of the elderly population. Over the past …
Inhibition of NaV1.8 prevents atrial arrhythmogenesis in human and mice
S Pabel, S Ahmad, P Tirilomis, T Stehle… - Basic Research in …, 2020 - Springer
Pharmacologic approaches for the treatment of atrial arrhythmias are limited due to side
effects and low efficacy. Thus, the identification of new antiarrhythmic targets is of clinical …
effects and low efficacy. Thus, the identification of new antiarrhythmic targets is of clinical …
A Mechanistic Clinical Trial Using (R)- Versus (S)-Propafenone to Test RyR2 (Ryanodine Receptor) Inhibition for the Prevention of Atrial Fibrillation Induction
MB Shoemaker, ZT Yoneda, DM Crawford… - Circulation …, 2022 - Am Heart Assoc
Background: Experimental data suggest ryanodine receptor-mediated intracellular calcium
leak is a mechanism for atrial fibrillation (AF), but evidence in humans is still needed …
leak is a mechanism for atrial fibrillation (AF), but evidence in humans is still needed …
[HTML][HTML] Simulation of ectopic pacemakers in the heart: multiple ectopic beats generated by reentry inside fibrotic regions
BG de Barros, RW dos Santos, M Lobosco… - BioMed research …, 2015 - ncbi.nlm.nih.gov
The inclusion of nonconducting media, mimicking cardiac fibrosis, in two models of cardiac
tissue produces the formation of ectopic beats. The fraction of nonconducting media in …
tissue produces the formation of ectopic beats. The fraction of nonconducting media in …
Opportunities and challenges of current electrophysiology research: a plea to establish 'translational electrophysiology'curricula
Cardiac electrophysiology has evolved into an important subspecialty in cardiovascular
medicine. This is in part due to the significant advances made in our understanding and …
medicine. This is in part due to the significant advances made in our understanding and …
Ambulatory cardiac arrhythmias in relation to mild hypokalaemia and prognosis in community dwelling middle-aged and elderly subjects
N Mattsson, G Sadjadieh, P Kumarathurai… - Europace, 2016 - academic.oup.com
Aims Severe hypokalaemia can aggravate arrhythmia tendency and prognosis, but less is
known about risk of mild hypokalaemia, which is a frequent finding. We examined the …
known about risk of mild hypokalaemia, which is a frequent finding. We examined the …
Atrial remodeling in permanent atrial fibrillation: mechanisms and pharmacological implications
DM Muntean, Z Kohajda, T Fazekas… - Journal of Clinical and …, 2013 - real.mtak.hu
Atrial fibrillation (AF), the most prevalent rhythm disorder in clinical practice, is currently
significantly contributing to morbidity and mortality of the ageing population. In the past …
significantly contributing to morbidity and mortality of the ageing population. In the past …
Mild hypokalemia and supraventricular ectopy increases the risk of stroke in community-dwelling subjects
N Mattsson, P Kumarathurai, BS Larsen, OW Nielsen… - Stroke, 2017 - Am Heart Assoc
Background and Purpose—Stroke is independently associated with the common conditions
of hypokalemia and supraventricular ectopy, and we hypothesize that the combination of …
of hypokalemia and supraventricular ectopy, and we hypothesize that the combination of …
New antiarrhythmic targets in atrial fibrillation
Atrial fibrillation (AF) is the most common cardiac arrhythmia in developed countries. AF is
associated with increased mortality and morbidity due to thromboembolism, stroke and …
associated with increased mortality and morbidity due to thromboembolism, stroke and …