Application of animal models in cancer research: recent progress and future prospects
Z Li, W Zheng, H Wang, Y Cheng, Y Fang… - Cancer management …, 2021 - Taylor & Francis
Animal models refers to the animal experimental objects and related materials that can
simulate human body established in medical research. As the second-largest disease in …
simulate human body established in medical research. As the second-largest disease in …
[HTML][HTML] Zebrafish xenograft as a tool for the study of colorectal cancer: a review
CM Fontana, H Van Doan - Cell Death & Disease, 2024 - nature.com
Colorectal cancer (CRC) is the second leading cause of cancer-related death, mostly due to
metastatic disease and the fact that many patients already show signs of metastasis at the …
metastatic disease and the fact that many patients already show signs of metastasis at the …
[HTML][HTML] Effect of miR-34a on the expression of clock and clock-controlled genes in DLD1 and Lovo human cancer cells with different backgrounds with respect to p53 …
R Moravčík, S Olejárová, J Zlacká, I Herichová - Plos one, 2023 - journals.plos.org
The small non-coding RNA miR-34a is a p53-regulated miRNA that acts as a tumour
suppressor of colorectal cancer (CRC). Oncogenesis is also negatively influenced by …
suppressor of colorectal cancer (CRC). Oncogenesis is also negatively influenced by …
[HTML][HTML] Enhanced anti-cancer effects of oestrogen and progesterone co-therapy against colorectal cancer in males
Although ovarian sex steroids could have protective roles against colorectal cancer (CRC) in
women, little is currently known about their potential anti-tumorigenic effects in men. Hence …
women, little is currently known about their potential anti-tumorigenic effects in men. Hence …
[HTML][HTML] Estrogen receptors in colorectal cancer: Facts, novelties and perspectives
I Ditonno, G Losurdo, M Rendina, M Pricci, B Girardi… - Current …, 2021 - mdpi.com
Colorectal cancer (CRC) is the second cause of cancer-related death in both sexes
worldwide. As pre-menopausal women are less likely to develop CRC compared to age …
worldwide. As pre-menopausal women are less likely to develop CRC compared to age …
[HTML][HTML] In vitro and vivo identification, metabolism and action of xenoestrogens: An overview
LH Wang, LR Chen, KH Chen - International Journal of Molecular …, 2021 - mdpi.com
Xenoestrogens (XEs) are substances that imitate endogenous estrogens to affect the
physiologic functions of humans or other animals. As endocrine disruptors, they can be …
physiologic functions of humans or other animals. As endocrine disruptors, they can be …
[HTML][HTML] Identification of a novel five-gene signature as a prognostic and diagnostic biomarker in colorectal cancers
S Ghatak, SF Mehrabi, LM Mehdawi… - International Journal of …, 2022 - mdpi.com
Colorectal cancer (CRC) is one of the leading causes of cancer-related mortality worldwide.
The current TNM (Tumor, Node, and Metastasis) classification approach is suboptimal in …
The current TNM (Tumor, Node, and Metastasis) classification approach is suboptimal in …
High PGD2 receptor 2 levels are associated with poor prognosis in colorectal cancer patients and induce VEGF expression in colon cancer cells and migration in a …
Background Despite intense research, the prognosis for patients with advanced colorectal
cancer (CRC) remains poor. The prostaglandin D2 receptors DP1 and DP2 are explored …
cancer (CRC) remains poor. The prostaglandin D2 receptors DP1 and DP2 are explored …
[HTML][HTML] Delineating the role of nuclear receptors in colorectal cancer, a focused review
Colorectal cancer (CRC) stands as one of the most prevalent form of cancer globally,
causing a significant number of deaths, surpassing 0.9 million in the year 2020. According to …
causing a significant number of deaths, surpassing 0.9 million in the year 2020. According to …
[HTML][HTML] Profiling estrogen, progesterone, and androgen receptors in colorectal cancer in relation to gender, menopausal status, clinical stage, and tumour sidedness
Background Although estrogen (ERα/ERβ), progesterone (PGR), and androgen (AR)
receptors are pathologically altered in colorectal cancer (CRC), their simultaneous …
receptors are pathologically altered in colorectal cancer (CRC), their simultaneous …