Oxytocin, vasopressin, and social behavior: from neural circuits to clinical opportunities

N Rigney, GJ de Vries, A Petrulis, LJ Young - Endocrinology, 2022 - academic.oup.com
Oxytocin and vasopressin are peptide hormones secreted from the pituitary that are well
known for their peripheral endocrine effects on childbirth/nursing and blood pressure/urine …

[HTML][HTML] The brain-body disconnect: A somatic sensory basis for trauma-related disorders

BE Kearney, RA Lanius - Frontiers in neuroscience, 2022 - frontiersin.org
Although the manifestation of trauma in the body is a phenomenon well-endorsed by
clinicians and traumatized individuals, the neurobiological underpinnings of this …

Adolescent sleep shapes social novelty preference in mice

WJ Bian, CL Brewer, JA Kauer, L de Lecea - Nature neuroscience, 2022 - nature.com
Sleep disturbances frequently occur in neurodevelopmental disorders such as autism, but
the developmental role of sleep is largely unexplored, and a causal relationship between …

[HTML][HTML] Social isolation and the brain: effects and mechanisms

Y Xiong, H Hong, C Liu, YQ Zhang - Molecular psychiatry, 2023 - nature.com
An obvious consequence of the coronavirus disease (COVID-19) pandemic is the worldwide
reduction in social interaction, which is associated with many adverse effects on health in …

Detection, processing and reinforcement of social cues: regulation by the oxytocin system

R Menon, ID Neumann - Nature Reviews Neuroscience, 2023 - nature.com
Many social behaviours are evolutionarily conserved and are essential for the healthy
development of an individual. The neuropeptide oxytocin (OXT) is crucial for the fine-tuned …

[HTML][HTML] Touch neurons underlying dopaminergic pleasurable touch and sexual receptivity

LJ Elias, IK Succi, MD Schaffler, W Foster, MA Gradwell… - Cell, 2023 - cell.com
Pleasurable touch is paramount during social behavior, including sexual encounters.
However, the identity and precise role of sensory neurons that transduce sexual touch …

Molecular and neural basis of pleasant touch sensation

B Liu, L Qiao, K Liu, J Liu, TJ Piccinni-Ash, ZF Chen - Science, 2022 - science.org
Pleasant touch provides emotional and psychological support that helps mitigate social
isolation and stress. However, the underlying mechanisms remain poorly understood. Using …

[HTML][HTML] A systematic review and multivariate meta-analysis of the physical and mental health benefits of touch interventions

J Packheiser, H Hartmann, K Fredriksen… - Nature Human …, 2024 - nature.com
Receiving touch is of critical importance, as many studies have shown that touch promotes
mental and physical well-being. We conducted a pre-registered (PROSPERO …

[HTML][HTML] Bridging skin, brain, and behavior to understand pleasurable social touch

LJ Elias, I Abdus-Saboor - Current Opinion in Neurobiology, 2022 - Elsevier
Social touch—the affiliative skin-to-skin contact between individuals—can rapidly evoke
emotions of comfort, pleasure, or calm, and is essential for mental and physical well-being …

[HTML][HTML] Neural mechanisms of comforting: Prosocial touch and stress buffering

KY Lim, W Hong - Hormones and Behavior, 2023 - Elsevier
Comforting is a crucial form of prosocial behavior that is important for maintaining social
unity and improving the physical and emotional well-being of social species. It is often …