The blood-brain barrier (BBB) is vital for maintaining brain homeostasis by enabling an
exquisite control of exchange of compounds between the blood and the brain parenchyma …

Nanotechnology is an area of growing public interest. Its attractiveness stems from the
promise offered socially and economically by the recent significant advances in …

Initial recruitment of leukocytes in inflammation associated with diseases such as multiple
sclerosis (MS), ischemic stroke, and HIV-related dementia, takes place across intact, but …

The blood-brain barrier (BBB) plays a critical role in normal physiology of the central
nervous system by regulating what reaches the brain from the periphery. The BBB also plays …

Successful T cell immunotherapy for brain cancer requires that the T cells can access
tumour tissues, but this has been difficult to achieve. Here we show that, in contrast to …

Multiple sclerosis is an autoimmune disease characterized by multifocal areas of
inflammation and demyelination within the central nervous system. The mechanism that …

Nipah virus (NiV), a zoonotic paramyxovirus, is highly contagious in swine, and can cause
fatal infections in humans following transmission from the swine host. The main viral targets …

Endothelial dysfunction is recognized as one of the leading factors in the pathogenesis of
diseases of the central nervous system of various etiologies. Numerous studies have shown …

Background: Long-term therapy with natalizumab increases the risk of progressive multifocal
leukoencephalopathy (PML). Objectives: We present a patient study through therapy, the …

Introduction Systemic delivery of bone marrow-derived mesenchymal stem cells (MSC)
seems to be of benefit in the treatment of multiple sclerosis (MS), an autoimmune disease of …