[HTML][HTML] Ribosome biogenesis in disease: new players and therapeutic targets
L Jiao, Y Liu, XY Yu, X Pan, Y Zhang, J Tu… - … and Targeted Therapy, 2023 - nature.com
The ribosome is a multi-unit complex that translates mRNA into protein. Ribosome
biogenesis is the process that generates ribosomes and plays an essential role in cell …
biogenesis is the process that generates ribosomes and plays an essential role in cell …
[HTML][HTML] New insight into circRNAs: characterization, strategies, and biomedical applications
XY Feng, SX Zhu, KJ Pu, HJ Huang, YQ Chen… - … Hematology & Oncology, 2023 - Springer
Circular RNAs (circRNAs) are a class of covalently closed, endogenous ncRNAs. Most
circRNAs are derived from exonic or intronic sequences by precursor RNA back-splicing …
circRNAs are derived from exonic or intronic sequences by precursor RNA back-splicing …
[HTML][HTML] The circular RNA circSPARC enhances the migration and proliferation of colorectal cancer by regulating the JAK/STAT pathway
J Wang, Y Zhang, H Song, H Yin, T Jiang, Y Xu, L Liu… - Molecular cancer, 2021 - Springer
Abstract Background Noncoding RNAs such as circular RNAs (circRNAs) are abundant in
the human body and influence the occurrence and development of various diseases …
the human body and influence the occurrence and development of various diseases …
[HTML][HTML] HNRNPL induced circFAM13B increased bladder cancer immunotherapy sensitivity via inhibiting glycolysis through IGF2BP1/PKM2 pathway
J Lv, K Li, H Yu, J Han, J Zhuang, R Yu… - Journal of Experimental …, 2023 - Springer
Background The response rate to immunotherapy in patients with bladder cancer (BCa)
remains relatively low. Considering the stable existence and important functions in tumour …
remains relatively low. Considering the stable existence and important functions in tumour …
MPCLCDA: predicting circRNA–disease associations by using automatically selected meta-path and contrastive learning
W Liu, T Tang, X Lu, X Fu, Y Yang… - Briefings in …, 2023 - academic.oup.com
Circular RNA (circRNA) is closely associated with human diseases. Accordingly, identifying
the associations between human diseases and circRNA can help in disease prevention …
the associations between human diseases and circRNA can help in disease prevention …
[HTML][HTML] Chemotherapy-induced exosomal circBACH1 promotes breast cancer resistance and stemness via miR-217/G3BP2 signaling pathway
Background Chemoresistance involves metastasis and aggressiveness of breast cancer
(BC). Chemotherapy-elicited exosomes have been reported to be associated with drug …
(BC). Chemotherapy-elicited exosomes have been reported to be associated with drug …
[HTML][HTML] Epigenetic alterations and inflammation as emerging use for the advancement of treatment in non-small cell lung cancer
Lung cancer remains one of the most common malignancies in the world. Nowadays, the
most common lung cancer is non-small cell lung cancer (NSCLC), namely …
most common lung cancer is non-small cell lung cancer (NSCLC), namely …
[HTML][HTML] New molecular mechanisms and clinical impact of circRNAs in human cancer
G Fontemaggi, C Turco, G Esposito, S Di Agostino - Cancers, 2021 - mdpi.com
Simple Summary Circular RNAs (circRNAs) belong to a new class of non-coding RNAs
implicated in cellular physiological functions but also in the evolution of various human …
implicated in cellular physiological functions but also in the evolution of various human …
[HTML][HTML] A novel protein encoded by ZCRB1-induced circHEATR5B suppresses aerobic glycolysis of GBM through phosphorylation of JMJD5
J Song, J Zheng, X Liu, W Dong, C Yang… - Journal of Experimental …, 2022 - Springer
Background RNA-binding proteins (RBPs) and circular RNAs (circRNAs) play important
roles in glioblastoma multiforme (GBM). Aerobic glycolysis is a metabolic characteristic of …
roles in glioblastoma multiforme (GBM). Aerobic glycolysis is a metabolic characteristic of …
A novel protein encoded by circASK1 ameliorates gefitinib resistance in lung adenocarcinoma by competitively activating ASK1-dependent apoptosis
Acquired resistance to growth factor receptor tyrosine kinase inhibitors limits the therapeutic
benefits gained by EGFR-mutant lung adenocarcinoma (LUAD) patients treated with …
benefits gained by EGFR-mutant lung adenocarcinoma (LUAD) patients treated with …